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GLP-1 drugs may leave food in stomach despite fasting, study warns

NCT ID NCT06814080

Knowledge-focused Sponsor: University of Arkansas Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is checking if people taking GLP-1 medications (like Ozempic) still have food or liquid in their stomachs before surgery, even after following fasting rules. Researchers will use ultrasound to look at the stomachs of 45 adults having elective surgery. The goal is to find out how common this is and help make surgery safer.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors create better fasting guidelines for patients on GLP-1 drugs, reducing the risk of aspiration during surgery.
What could go wrong
This is a small, early observational study with only 45 participants, so results may not apply to everyone. It does not test a treatment, so it won't directly change care yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 45 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All subjects on GLP-1 scheduled for elective surgery will be screened for recruitment. We will find prospective subjects via medical records review or through our preoperative evaluation team which is a standard of care and then contact the patients about the study. Subjects enrolled in the study will be treated as per normal practice for elective surgery.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Age ≥ 18 yr. ASA physical status I- III Elective surgery Exclusion Criteria: * Pregnancy * History of upper gastrointestinal disease or previous surgery on the esophagus, stomach or upper abdomen; * Documented abnormalities of the upper gastrointestinal tract such as gastric tumors; recent upper gastrointestinal bleeding (within the preceding 1 month). * Medicines that may delay gastric emptying (e.g., anticholinergic agents, opioid) * ASA class IV or above * Unable to understand English * Cardiac cases with low ejection fraction * Elderly patients above 65 years of age * Liver or renal transplant cases * Type 1 diabetes Patients on insulin or sulphonylurea medication

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pre-op gastric emptying

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Arkansas for Medical Science

    RECRUITING

    Little Rock, Arkansas, 72205, United States