Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Why do some Alzheimer's patients repeat themselves? a study digs into the Brain's memory glitch

NCT ID NCT07732842

Knowledge-focused Sponsor: Centre Hospitalier Esquirol Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Sep 11, 2026 · Updated 3 times

Summary

This study investigates repetitive behaviors—like repeating words or actions—in people with Alzheimer's disease. Researchers want to understand how common these behaviors are, what types occur, and whether they are linked to memory problems or lack of awareness of the condition. The study compares Alzheimer's patients with and without repetitive behaviors, as well as healthy volunteers, using questionnaires and memory tests.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help explain why some Alzheimer's patients develop repetitive behaviors and point toward better ways to manage them.
What could go wrong
This is an observational study, not a treatment trial, so it will not directly lead to new therapies. The findings may not apply to all Alzheimer's patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 103 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2021

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of: * 42 patients RB+ and 30 patients RB- patients recruited at the CMRR in Limoges and Nantes during their follow-up appointments for Alzheimer's disease. * 30 healthy subjects who are caregivers for patients monitored at the CMRR in Limoges. * And the patient with AA anterograde amnesia, who was recruited as part of his follow-up at the CMRR in Limoges for his severe anterograde amnesia caused by brain damage to the fornix pillars following complications from neurosurgery.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: I- RB+ (n=42) and RB- (n=30) groups : 1. MMSE \> 20 2. 1 reliable family caregiver identified per patient 3. Patients under legal protection (guardianship/curatorship) or not 4. Selection: 4.a. AD patients with an SRI score \> 0 will constitute the RB+ subgroup. 4.b. Only the first 30 patients included will undergo V2, V3, and V4. The first 30 AD patients included with an SRI score = 0 will constitute the RB- subgroup. II- Control group: healthy subjects (n=30) 1. Healthy subjects 2. MMSE ≥ 26/30 3. Men and women matched to AD patients in terms of age and sociocultural level. 4. Healthy subjects will be included by the CMRR in Limoges III- Control group: Patient with anterograde amnesia (AA) (n=1): 1. The patient with anterograde amnesia is a patient who participated in the ANISAAFORNIX study (another study submitted by the investigator) and is included in this study due to rich RB symptomatology. He is a 54-year-old man with lesions of the fornix following complications from neurosurgery, which led to severe anterograde amnesia. This patient does not have AD. 2. This patient is under legal protection (guardianship). 3. Patient monitored and included at the CMRR in Limoges. Exclusion Criteria: I- RB+ and RB- groups and healthy subjects: 1. Isolated participants (without an identified caregiver) (RB+ and RB- groups) 2. Participants must not have a history of alcohol or other substance dependence in the past 12 months. 3. Participants must not have any other neurological condition (with the exception of patients with AA anterograde amnesia). Any history of moderate to severe head trauma, stroke, or developmental disorders is a criterion for exclusion.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Alzheimer disease are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

agnosia Alzheimer disease anosognosia anterograde amnesia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimer disease Anosognosia Anterograde amnesia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Esquirol Hospital Center

    RECRUITING

    Limoges, New Aquitaine, 87025, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.