Breathing Low-Oxygen air may boost hand recovery after spinal cord injury
NCT ID NCT03780829
First seen Feb 25, 2026
Summary
This early-phase study tested whether breathing mild low-oxygen air (acute intermittent hypoxia) combined with hand exercise training could improve grip and pinch strength in people with chronic cervical spinal cord injury. The study also tested the drug D-cycloserine to see if it could enhance the effects. The trial was terminated early, so the findings are limited, but the goal was to find new ways to promote nerve repair and improve daily function.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Edward Hines Jr. VA Hospital, Hines, IL
Hines, Illinois, 60141-3030, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
D-cycloserine
What this could lead to
If successful, this approach could point toward a way to improve hand and arm function after spinal cord injury by combining breathing treatments with exercise.
What could go wrong
This was a very early, small study that was terminated, so results are limited. The treatment is still experimental and may not work in people.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.