Could a blood pressure cuff boost exercise benefits for seniors?
NCT ID NCT06476288
First seen Jun 27, 2026 · Last updated Sep 16, 2026 · Updated 4 times
Summary
This study tests whether a technique called remote ischemic conditioning (RIC) — using a blood pressure cuff to briefly restrict blood flow to the arm — can make low-intensity exercise more effective for adults over 65 with mobility problems. Twenty participants will do light resistance training three times a week for six weeks, with some also receiving RIC. The goal is to see if this approach is feasible and acceptable, and whether it can improve muscle strength, physical function, and resilience.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Remote ischemic conditioning (RIC) — a technique using a blood pressure cuff to temporarily restrict blood flow to the arm, combined with low-intensity resistance exercise
- What this could lead to
- If it works, this could point toward a simple, low-cost way to boost the benefits of exercise for older adults, helping them stay mobile and independent.
- What could go wrong
- This is a very small, early feasibility study with only 20 participants, so results may not apply to everyone. The approach is experimental and may not improve strength or mobility as hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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19 people
The number who actually took part.
- Started
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Sep 2024
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age: ≥ 65 years and referred to an exercise program for functional decline, deconditioning, or fall risk 2. Exercises ≤ 2x/week on a regular interval Exclusion Criteria: 1. Unstable heart disease as determined by the investigator or study physician 2. History of any orthopaedic, neurologic, or metabolic condition that would contraindicate exercise testing/training as determined by the investigator 3. Cognitive inability to follow directions and safely participate in exercise
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Duke University
Durham, North Carolina, 27710, United States
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