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Could a blood pressure cuff boost exercise benefits for seniors?

NCT ID NCT06476288

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 16, 2026 · Updated 4 times

Summary

This study tests whether a technique called remote ischemic conditioning (RIC) — using a blood pressure cuff to briefly restrict blood flow to the arm — can make low-intensity exercise more effective for adults over 65 with mobility problems. Twenty participants will do light resistance training three times a week for six weeks, with some also receiving RIC. The goal is to see if this approach is feasible and acceptable, and whether it can improve muscle strength, physical function, and resilience.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Remote ischemic conditioning (RIC) — a technique using a blood pressure cuff to temporarily restrict blood flow to the arm, combined with low-intensity resistance exercise
What this could lead to
If it works, this could point toward a simple, low-cost way to boost the benefits of exercise for older adults, helping them stay mobile and independent.
What could go wrong
This is a very small, early feasibility study with only 20 participants, so results may not apply to everyone. The approach is experimental and may not improve strength or mobility as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

19 people

The number who actually took part.

Started

Sep 2024

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age: ≥ 65 years and referred to an exercise program for functional decline, deconditioning, or fall risk 2. Exercises ≤ 2x/week on a regular interval Exclusion Criteria: 1. Unstable heart disease as determined by the investigator or study physician 2. History of any orthopaedic, neurologic, or metabolic condition that would contraindicate exercise testing/training as determined by the investigator 3. Cognitive inability to follow directions and safely participate in exercise

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Conditions

The condition(s) this trial relates to.

Frailty Mobility Limitation Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University

    Durham, North Carolina, 27710, United States

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Other studies related to the condition(s) this trial covers.