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Robot vs. electromagnetic navigation: which lung biopsy tool wins?

NCT ID NCT06654271

Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two advanced bronchoscopy techniques—robotic assisted bronchoscopy and electromagnetic navigation bronchoscopy—to see which one more accurately diagnoses lung lesions. About 440 adults scheduled for a lung biopsy will be randomly assigned to one method. The main goal is to measure how often each method successfully collects tissue that explains the lesion.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Robotic assisted bronchoscopy (RAB) and electromagnetic navigation bronchoscopy (ENB) devices
What this could lead to
If one method proves clearly better, it could become the standard approach for diagnosing lung nodules, improving accuracy and reducing repeat procedures.
What could go wrong
This is a pragmatic trial comparing two existing technologies, so it is not testing a new treatment. The results may show no significant difference, or one method may only be better in specific cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

440 people

The number who actually took part.

Started

Nov 2024

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ≥ 18 years of age at time of bronchoscopy * Scheduled for navigational bronchoscopy for the evaluation of a pulmonary lesion Exclusion Criteria: * Patient declines to participate * Patients enrolled in another trial which requires the use of one specific navigational platform

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Conditions

The condition(s) this trial relates to.

pulmonary coin lesion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung nodule, solitary Peripheral pulmonary lesion

Contacts and locations

Locations

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

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