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Could less radiation be enough for some advanced head and neck cancers?

NCT ID NCT07328841

First seen Jan 11, 2026 · Last updated May 22, 2026 · Updated 16 times

Summary

This study is for people with advanced nasopharyngeal cancer (a type of head and neck cancer) whose tumors shrink significantly after initial chemotherapy and immunotherapy. It tests whether a lower dose of radiation therapy is as effective as the standard dose, with fewer side effects. About 456 participants will be randomly assigned to receive either reduced-dose or conventional-dose radiation, along with standard chemotherapy and immunotherapy. The goal is to see if the lower dose can still prevent the cancer from coming back or spreading.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Center of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

  • Cancer Hospital of Shantou University Medical College

    RECRUITING

    Shantou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Central South University Cancer Hospital

    RECRUITING

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-sen University cancer center

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Fifth Affiliated Hospital of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, 516000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Fifth Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Guangdong, Zhuhai, 519000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The People's Hospital of Guangxi Zhuang Autonomous Region

    RECRUITING

    Nanning, Guangxi, 530021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Sun Yat-sen University (SYSU)

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

  • Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-••••

  • Wuzhou Red Cross Hospital

    RECRUITING

    Wuzhou, Guangxi, China

    Contact Phone: •••-•••-••••

  • Xiangya Hospital of Central South University

    RECRUITING

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhongshan City People's Hospital

    RECRUITING

    Zhongshan, Guangdong, China

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.