Milder chemo before transplant may help older blood cancer patients live longer without relapse
NCT ID NCT05436561
First seen Mar 23, 2026 · Last updated Jun 01, 2026 · Updated 4 times
Summary
This study tests a reduced-intensity chemotherapy combination (fludarabine, busulfan, melphalan) given before a stem cell transplant in people aged 55 and older with myeloid cancers like AML, MDS, or CMML. The goal is to see if this gentler approach can help patients stay free of cancer longer while reducing side effects. About 61 participants will be enrolled across multiple centers.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Blood & Marrow Transplantation Center, RuiJin Hospital
RECRUITINGShanghai, Shanghai Municipality, 200025, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanghai No 6 Hospital
RECRUITINGShanghai, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.