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New drug combo aims to shrink rectal tumors without radiation

NCT ID NCT07127497

Summary

This study is testing whether combining the immunotherapy drug sintilimab with standard chemotherapy (XELOX) before surgery can effectively shrink tumors in people with locally advanced rectal cancer. The approach specifically aims to avoid radiation therapy, which can have significant side effects. Researchers will measure how well the tumors respond and monitor safety in 50 participants.

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Contacts and locations

Locations

  • The First Affiliated Hospital of Anhui Medical University

    Hefei, Anhui, 230022, China

Conditions

Explore the condition pages connected to this study.