New hope for rectal cancer: avoiding surgery with stronger chemo combo
NCT ID NCT02514278
First seen May 15, 2026 · Last updated May 18, 2026 · Updated 1 time
Summary
This study tested whether giving a stronger chemotherapy combination (Folfirinox) before standard radiation and chemo could help more people with early-stage rectal cancer avoid surgery and keep their rectum. About 218 adults with small, low-lying rectal tumors took part. The goal was to see if the extra chemo increased the chance of preserving the organ and avoiding a stoma one year later.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Département de chirurgie digestive, Institut Gustave Roussy
Villejuif, France
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GH Paris Saint Joseph
Paris, France
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Service d'Oncologie et Radiothérapie, Centre Azuréen de Cancérologie
Mougins, France
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Service de Chirurgie Digestive et Oncologique, Hôpital Bicêtre - APHP
Paris, France
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Service de Chirurgie Digestive, CHU Amiens Picardie
Amiens, France
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Service de Chirurgie Digestive, CHU Carémeau - Nîmes
Nîmes, France
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Service de Chirurgie Digestive, CHU Estaing - CHRU Clermont Ferrand
Clermont-Ferrand, France
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Service de Chirurgie Digestive, CHU de Besançon
Besançon, France
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Service de Chirurgie Digestive, CHU de la Timone - Marseille
Marseille, France
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Service de Chirurgie Digestive, Centre Georges François Leclerc - Dijon
Dijon, France
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Service de Chirurgie Digestive, Centre Léon Bérard - Lyon
Lyon, France
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Service de Chirurgie Digestive, Centre Oscar Lambret - Lille
Lille, France
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Service de Chirurgie Digestive, Hôpital Albert Michallon - CHU de Grenoble
La Tronche, France
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Service de Chirurgie Digestive, Hôpital Beaujon - APHP
Clichy, France
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Service de Chirurgie Digestive, Hôpital Charles Nicolle - CHU de Rouen
Rouen, France
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Service de Chirurgie Digestive, Hôpital Haut-Lévêque - CHU de Bordeaux
Bordeaux, France
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Service de Chirurgie Digestive, Hôpital Lyon Sud - CHU Lyon
Lyon, France
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Service de Chirurgie Digestive, Hôpital Pontchaillou - CHU Rennes
Rennes, France
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Service de Chirurgie Digestive, Hôpital Purpan - CHU de Toulouse
Toulouse, France
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Service de Chirurgie Digestive, Hôpital Saint-Antoine - APHP
Paris, France
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Service de Chirurgie Digestive, Hôpital Saint-Louis - APHP Paris
Paris, France
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Service de Chirurgie Digestive, Hôpital les Diaconnesses
Paris, France
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Service de Chirurgie Digestive, Hôtel Dieu - CHU de Nantes
Nantes, France
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Service de Chirurgie Digestive, Institut Bergonié
Bordeaux, France
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Service de Chirurgie Digestive, Institut Paoli Calmette - Marseille
Marseille, France
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Service de Chirurgie Digestive, Institut du Cancer de Montpellier
Montpellier, France
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Service de Chirurgie Digestive,Institut de Cancérologie de Lorraine
Nancy, France
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Service de Chirurgie Digestives, Hôpital Européen de Marseille
Marseille, France
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Service de chirurgie digestive, CHRU de Nancy -Hôpital de Brabois
Vandœuvre-lès-Nancy, France
Conditions
Explore the condition pages connected to this study.