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Which anesthesia wears off faster? new trial aims to find out

NCT ID NCT06275087

Knowledge-focused Sponsor: Clinical Hospital Centre Zagreb Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial compares how quickly patients recover from two types of general anesthesia during mouth tumor surgery. 42 adults will receive either propofol (TIVA) or sevoflurane (inhalation). Researchers will measure recovery quality, muscle strength, nausea, and shivering up to 30 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
propofol and sevoflurane
What this could lead to
If it works, this could help doctors choose the best anesthesia method for faster recovery after oral surgery.
What could go wrong
This is a small, early-stage trial with only 42 participants, so results may not apply to everyone. It compares two existing drugs, not a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 42 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2024

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Criteria for patient inclusion are: * patients older than 18 years * ASA status 1-2, * Patients who have an indication for an intraoral surgical procedure longer than 30 minutes. * Surgical interventions on the soft tissues of the mouth, intraoral excision of tumors, operated through the transoral route * Patients who agreed to the research and signed the consent The exclusion criteria are: * ASA status 3 and higher, * The need for postoperative care in the ICU, * Surgery lasting more than 2 hours, * Surgical procedures that in the operative plan include injuries to the grip of the masticatory muscles, the masticatory muscles themselves, and procedures on the bone, and thus may result in a difference in the strength of the bite. Masticatory muscles are defined as musculus pterygoideus lateralis, musculus pterygoideus medialis, musculus temporalis and musculus masseter. * Surgical procedures on the bone where the bite force test alone could cause injury * Patients with diseases of the neuromuscular junction and muscle diseases, myopathy, dystrophy * Patients taking medications that can cause myopathy or muscle weakness * Known allergies to drugs used in the trial, * Refusing to participate

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Conditions

The condition(s) this trial relates to.

oral cavity neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intraoral tumor

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Hospital Centre Zagreb

    RECRUITING

    Zagreb, 10000, Croatia