Herbal blend shows promise for quick cough relief in new trial
NCT ID NCT07420491
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether Reconyl, a mix of four Indonesian herbs, can safely ease acute cough better than a placebo. 144 adults with sudden cough took either Reconyl or a placebo three times daily for 7 days. Researchers measured changes in cough severity and quality of life, along with kidney and liver function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Reconyl (a blend of four Indonesian herbs: Vitex trifolia, ginger, Abrus precatorius, and Phaleria macrocarpa)
- What this could lead to
- If it works, this could provide a natural, side-effect-free option for relieving acute cough.
- What could go wrong
- This is a small, completed Phase 3 trial with only 144 participants. The herbal blend may not work better than a placebo, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
-
144 people
The number who actually took part.
- Started
-
Jun 2025
- Finished
-
Oct 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 50 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Signed informed consent from the subject or the subject's legally acceptable representatives (must obtained before any trial related activities) 2. Male or female subjects, aged 18-50 years at screening 3. Experience acute cough, defined as sudden onset dominant or main symptom of acute or worsened cough, with or without sputum, in the span of 72 hours, avoiding prescription and non-prescription cough-relieving medications (e.g. antitusives such as codeine-based cough supressants or dextromethorphan HBr, and mucolytics such as N-acetylsistein, Bromhexin and Ambroxol), within 24 hours before entering the study. 4. The condition of the patient does not have any illness other than acute cough that could possibly interfere with the study evaluation, such as chronic obstructive pulmonary disease (COPD), suspect GERD, rhinitis, asthma, tuberculosis (TB), and pneumonia. 5. Cooperative and able to fill out study material Exclusion Criteria: 1. Subject with febrile within 24 hours before screening, or has body temperature ≥ 38°C during screening visit 2. Personal/family history of allergy or hypersensitivity or contradiction to any component of the drugs 3. History or clinical evidence of immunosuppression according to investigator assessment, or currently under treatment with immunosuppressive agents 4. Participation in any other trial less than 90 days before 5. Pregnancy or lactation 6. History of drug or alcohol abuse within 12 months prior to screening
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cough are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Velia Medika Primary Care Clinic
Jakarta, Jakarta Special Capital Region, 12430, Indonesia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could skipping the breathing tube ease recovery after throat surgery?
- Chili compound put to the test as a cough silencer
- Timing the dose: a new strategy to stop coughing under anesthesia?
- Can a simple breathing test unlock the secrets of chronic cough?
- Could a new dissolving tablet quiet coughs? safety trial begins
- New pill aims to silence chronic cough that Won't quit