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No more charging: new implant aims to ease bladder and bowel leaks

NCT ID NCT06186765

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 37 times

Summary

This study is testing a new, recharge-free nerve stimulator (Axonics SNM system) in 144 adults with overactive bladder or fecal incontinence. The device is implanted to stimulate sacral nerves and improve control. Researchers will measure quality of life and symptom changes over one year, along with safety.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Adult Pediatric Urology & Urogynecology

    Omaha, Nebraska, 68114, United States

  • Atrium Health

    Macon, Georgia, 31201, United States

  • Bristol Urological Institute

    Bristol, BS105NB, United Kingdom

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • East Coast Institute of Research

    Jacksonville, Florida, 32216, United States

  • Erasmus Medical Center

    Rotterdam, Netherlands

  • Florida Bladder Institute

    Naples, Florida, 34109, United States

  • Florida Gulf Clinical Research

    Bradenton, Florida, 34205, United States

  • Hartford Healthcare

    Waterford, Connecticut, 06385, United States

  • Houston Colon

    Houston, Texas, 77030, United States

  • Minnesota Urology

    Coon Rapids, Minnesota, 55433, United States

  • Northern General Hospital

    Sheffield, S5 7AU, United Kingdom

  • Queen Elizabeth Hospital

    Birmingham, B15 2TH, United Kingdom

  • Southern Shores Urogynecology

    Myrtle Beach, South Carolina, 29572, United States

  • The Oregon Clinic

    Portland, Oregon, 97225, United States

  • University College London Hospital

    London, W1G 8PH, United Kingdom

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Axonics recharge-free sacral neuromodulation (SNM) system (Model 4101)

What this could lead to

If successful, this device could offer a more convenient, long-term option for managing bladder and bowel control without needing to recharge the implant.

What could go wrong

This is a single-arm, non-randomized study with no placebo group, so results may be less reliable. The device may not work for everyone, and risks include infection or device-related complications.

Conditions

The condition(s) this trial relates to.

Fecal Incontinence overactive bladder Urinary Incontinence, Urge

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.