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How does venetoclax work for CLL patients in everyday clinics?

NCT ID NCT03342144

Knowledge-focused Sponsor: AbbVie Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This study is tracking 500 people with chronic lymphocytic leukemia (CLL) who are taking venetoclax, either alone or with other drugs, as part of their normal care in Austria, Germany, and Switzerland. Researchers want to see how well the treatment works in real-life settings and what costs are involved. The study does not assign treatments—doctors prescribe based on local guidelines.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
venetoclax
What this could lead to
If successful, this study could provide real-world evidence on how effective venetoclax is for CLL patients outside of controlled trials.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by patient selection and varying treatment practices.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2017

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants with chronic lymphocytic leukemia (CLL) administering venetoclax per the local label.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Participant with chronic lymphocytic leukemia (CLL) who start venetoclax therapy can be included in the study if treated as specified in the local label for any specific line of treatment. Exclusion Criteria: \- None

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia leukemia neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic lymphocytic leukemia (CLL)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ambulantes Tumorzentrum Bremerhaven /ID# 224353

    COMPLETED

    Bremerhaven, Free Hanseatic City of Bremen, 27576, Germany

  • BAG Freiberg-Richter, Jacobasch, Illmer, Wolf /ID# 201532

    COMPLETED

    Dresden, Saxony, 01307, Germany

  • Bruederkrankenhaus St. Josef Paderborn /ID# 202600

    COMPLETED

    Paderborn, 33098, Germany

  • Caritas-Krankenhaus gGmbH /ID# 243212

    COMPLETED

    Bad Mergentheim, 97980, Germany

  • Centrum fuer Haematologie und Onkologie Bethanien /ID# 206701

    COMPLETED

    Frankfurt am Main, Hesse, 60389, Germany

  • Diakonieklinikum Schwaebisch Hall /ID# 206205

    COMPLETED

    Schwäbisch Hall, 74523, Germany

  • Drs. Tanzer, Chirca, Stoeberl /ID# 202613

    COMPLETED

    Bad Reichenhall, Bavaria, 83435, Germany

  • EOC Ospedale Regionale di Bellinzona e Valli /ID# 208782

    COMPLETED

    Bellinzona, Canton Ticino, 6500, Switzerland

  • Evangelisches Krankenhaus Hamm /ID# 206703

    COMPLETED

    Hamm, 59063, Germany

  • Evidia MVZ III Oncology Halle /ID# 218354

    COMPLETED

    Halle, Saxony-Anhalt, 06110, Germany

  • Friedrich-Ebert-Krankenhaus GmbH /ID# 206206

    COMPLETED

    Neumünster, Schleswig-Holstein, 24534, Germany

  • Gemeinschaftspraxis Dr. Heinrich und Prof. Bangerter /ID# 200950

    COMPLETED

    Augsburg, Bavaria, 86150, Germany

  • Haemato-Onkologie /ID# 205236

    COMPLETED

    Munich, Bavaria, 81241, Germany

  • Hanusch Krankenhaus /ID# 221151

    COMPLETED

    Vienna, 1140, Austria

  • Hämatologie und Onkologie /ID# 205247

    COMPLETED

    Kaiserslautern, Rhineland-Palatinate, 67655, Germany

  • Inselspital, Universitaetsspital Bern /ID# 210031

    COMPLETED

    Bern, 3010, Switzerland

  • Internistische Schwerpunktpraxen, Erlangen /ID# 200949

    COMPLETED

    Erlangen, Bavaria, 91052, Germany

  • KSW Kantonsspital Winterthur /ID# 211068

    COMPLETED

    Winterthur, Canton of Zurich, 8400, Switzerland

  • Kantonsspital Aarau AG /ID# 210034

    COMPLETED

    Aarau, Canton of Aargau, 5001, Switzerland

  • Kantonsspital Münsterlingen /ID# 210035

    COMPLETED

    Münsterlingen, Thurgau, 8596, Switzerland

  • Kantonsspital St. Gallen /ID# 223037

    COMPLETED

    Sankt Gallen, Canton of St. Gallen, 9007, Switzerland

  • Klinikum Frankfurt Hoechst /ID# 210048

    COMPLETED

    Frankfurt am Main, Hesse, 65929, Germany

  • Klinikum Idar-Oberstein GmbH /ID# 210046

    COMPLETED

    Idar-Oberstein, 55743, Germany

  • Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 221153

    ACTIVE_NOT_RECRUITING

    Salzburg, 5020, Austria

  • Luebecker Oncology Practice /ID# 200952

    COMPLETED

    Lübeck, Schleswig-Holstein, 23562, Germany

  • Luzerner Kantonsspital /ID# 210029

    COMPLETED

    Lucerne, Canton of Lucerne, 6000, Switzerland

  • MVZ Dres. Cordes & Partner /ID# 202598

    COMPLETED

    Frankfurt am Main, Hesse, 60596, Germany

  • MVZ Klinikum Mittelbaden GmbH /ID# 206207

    COMPLETED

    Baden-Baden, 76532, Germany

  • MVZ Onkologie GmbH /ID# 212376

    COMPLETED

    Hagen, 58095, Germany

  • MVZ am Klinikum Aschaffenburg Onkologie /ID# 201548

    COMPLETED

    Aschaffenburg, Bavaria, 63739, Germany

  • MVZ am Schlossgarten GmbH /ID# 210043

    COMPLETED

    Schwetzingen, 68723, Germany

  • MVZ der Paracelsus-Klinik /ID# 201541

    COMPLETED

    Osnabrück, Lower Saxony, 49076, Germany

  • MVZ f. Blut- u.Krebserkrankungen /ID# 206704

    COMPLETED

    Potsdam, Brandenburg, 14467, Germany

  • Med. Studiengesellschaft Nord West GmbH /ID# 201535

    COMPLETED

    Westerstede, Lower Saxony, 26655, Germany

  • Medizinische Universitaet Graz /ID# 221155

    COMPLETED

    Graz, Styria, 8010, Austria

  • OAZ Hannover /ID# 201538

    COMPLETED

    Hanover, Lower Saxony, 30171, Germany

  • OncoResearch Lerchenfeld GmbH /ID# 205237

    COMPLETED

    Hamburg, 22081, Germany

  • Onkologie Hof /ID# 201531

    COMPLETED

    Hof, Bavaria, 95028, Germany

  • Onkologie am Segelfliegerdamm /ID# 202603

    COMPLETED

    Berlin, 12487, Germany

  • Onkologische Gemeinschaftspraxis /ID# 205239

    COMPLETED

    Hamburg, 22767, Germany

  • Onkologische Kooperation Harz /ID# 201550

    COMPLETED

    Goslar, Lower Saxony, 38642, Germany

  • Onkologische Praxis /ID# 201545

    COMPLETED

    Stuttgart, Baden-Wurttemberg, 70174, Germany

  • Onkologische Praxis GbR /ID# 206705

    COMPLETED

    Porta Westfalica, 32457, Germany

  • Onkologische Schwerpunktpraxis /ID# 200953

    COMPLETED

    Berlin, 10707, Germany

  • Onkolologische Praxis Oldenburg /ID# 202607

    COMPLETED

    Oldenburg, Lower Saxony, 26121, Germany

  • Onkozentrum Dresden /ID# 202599

    COMPLETED

    Dresden, Saxony, 01127, Germany

  • Pioh Dres. Draube & Partner /ID# 239507

    COMPLETED

    Cologne, 50674, Germany

  • Praxis Dr. Klaproth/Cura /ID# 216413

    COMPLETED

    Neunkirchen, Saarland, 66538, Germany

  • Praxis Dr. Kreher /ID# 202604

    COMPLETED

    Bad Liebenwerda, Brandenburg, 04924, Germany

  • Praxis Dr. Stauch /ID# 202611

    COMPLETED

    Kronach, Bavaria, 96317, Germany

  • Praxis Dres. Decker/Lakner/Leithäuser /ID# 206208

    COMPLETED

    Rostock, 18057, Germany

  • Praxis Dres. Kiehl/Stein /ID# 210052

    COMPLETED

    Frankfurt (Oder), Brandenburg, 15236, Germany

  • Praxis Dres. Krober/Stosiek /ID# 206729

    COMPLETED

    Regensburg, State of Berlin, 93053, Germany

  • Praxis Dres. Plewe/Losem /ID# 202606

    COMPLETED

    Neuss, North Rhine-Westphalia, 41462, Germany

  • Praxis Dres. Prange-Krex/Mohm /ID# 210049

    COMPLETED

    Dresden, 01307, Germany

  • Praxis Dres. Tebbe/Mayer /ID# 206730

    COMPLETED

    Kassel, Hesse, 34125, Germany

  • Praxis Fuchs/Koehler /ID# 243215

    COMPLETED

    Langenhessen, 63225, Germany

  • Praxis am Volkspark /ID# 243195

    COMPLETED

    Berlin, 10715, Germany

  • Praxis fuer interdisziplinaere Onkolologie und Haematologie /ID# 206999

    COMPLETED

    Freiburg im Breisgau, 79110, Germany

  • Praxis für Hämatologie und Onkologie /ID# 241763

    COMPLETED

    Berlin, 10117, Germany

  • Réseau Hospitalier Neuchâtelois /ID# 227865

    RECRUITING

    Neuchâtel, Canton of Neuchâtel, 2000, Switzerland

  • Schwarzwald-Baar-Klinikum /ID# 208176

    COMPLETED

    Villingen-Schwenningen, Baden-Wurttemberg, 78052, Germany

  • Spital Thun /ID# 233714

    COMPLETED

    Thun, Canton of Bern, 3600, Switzerland

  • St. Georg Klinikum Eisenach gemeinnützige GmbH (GKE) /ID# 250200

    COMPLETED

    Eisenach, 99817, Germany

  • Stauferklinikum Schwaebisch Gmuend /ID# 201518

    COMPLETED

    Mutlangen, Baden-Wurttemberg, 73557, Germany

  • Studienbüro Kamal und Dorn GBR /ID# 234105

    COMPLETED

    Hanover, 30625, Germany

  • Studienzentrum Aschaffenburg /ID# 204125

    COMPLETED

    Aschaffenburg, Bavaria, 63739, Germany

  • Studienzentrum am Raschplatz /ID# 250180

    COMPLETED

    Hanover, 30161, Germany

  • Universitaetsklinikum St. Poelten /ID# 221152

    COMPLETED

    Sankt Pölten, Lower Austria, 3100, Austria

  • VK&K Studien GbR /ID# 202614

    COMPLETED

    Landshut, Bavaria, 84036, Germany

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Other studies related to the condition(s) this trial covers.