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New study aims to perfect radiation dose for liver cancer treatment

NCT ID NCT07345247

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a procedure called radiation segmentectomy for adults with liver cancer. Doctors deliver tiny radioactive resin beads directly to the tumor's blood supply to kill cancer cells while sparing healthy tissue. The goal is to find the best radiation dose for complete tumor shrinkage and to confirm the treatment is safe. 150 participants will be followed for at least 3 months after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Y-90 resin microspheres
What this could lead to
If successful, this could establish a standard dose for using resin microspheres in radiation segmentectomy, improving tumor control while minimizing liver damage.
What could go wrong
This is a single-center, non-randomized study with 150 participants. Results may not apply to all liver cancer patients, and there are risks of radiation-induced liver injury or incomplete tumor response.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Study population will include the patients who will receive radioembolization for radiation segmentectomy intent for primary or secondary liver tumors

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged ≥18 years * Underwent RE as a RS intent (have single or \<3 tumors in same or neighboring 2 segments) for the treatment of HCC or metastatic tumor to liver. * Presence of extrahepatic disease * Tumor size less than 8 cm * Child Pugh Score \<B9 Exclusion Criteria: * Presence of macrovascular invasion, * Presence of extrahepatic disease, * Cholangiocarcinoma or mixed HCC-cholangiocarcinoma * Not willing to attend follow-up visits.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    20 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Acibadem Adana Hospital

    RECRUITING

    Adana, Turkey (Türkiye)

  • Acibadem Izmir Hospital

    NOT_YET_RECRUITING

    Izmir, Turkey (Türkiye)

  • Adana City Hospital

    NOT_YET_RECRUITING

    Adana, Turkey (Türkiye)

  • Bilkent City Hospital

    NOT_YET_RECRUITING

    Ankara, Turkey (Türkiye)

  • Cam ve Sakura Education and Reseach Hospital

    RECRUITING

    Istanbul, Turkey (Türkiye)

  • Cukurova University

    NOT_YET_RECRUITING

    Adana, Turkey (Türkiye)

  • Ege University

    NOT_YET_RECRUITING

    Izmir, Turkey (Türkiye)

  • Erciyes University

    RECRUITING

    Kayseri, Turkey (Türkiye)

  • Gazi Yasargil Education and Research Hospital

    NOT_YET_RECRUITING

    Diyarbakır, Turkey (Türkiye)

  • Gulhane Education and Research Hospital

    NOT_YET_RECRUITING

    Ankara, Turkey (Türkiye)

  • Hacettepe University

    RECRUITING

    Ankara, Turkey (Türkiye)

  • Inonu University

    RECRUITING

    Malatya, Turkey (Türkiye)

  • Istanbul Unicersity Cerrahpasa Medical School

    NOT_YET_RECRUITING

    Istanbul, Turkey (Türkiye)

  • Istanbul University Capa Medical School

    RECRUITING

    Istanbul, Turkey (Türkiye)

  • Katip Celebi Education and Research Hospital

    RECRUITING

    Izmir, Turkey (Türkiye)

  • Kocaeli University

    NOT_YET_RECRUITING

    Kocaeli, Turkey (Türkiye)

  • Konya Selcuk University

    RECRUITING

    Konya, Turkey (Türkiye)

  • Marmara University

    RECRUITING

    Istanbul, Turkey (Türkiye)

  • Mersin City Hospital

    NOT_YET_RECRUITING

    Mersin, Turkey (Türkiye)

  • Pamukkale University

    NOT_YET_RECRUITING

    Denizli, Turkey (Türkiye)

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