New study aims to perfect radiation dose for liver cancer treatment
NCT ID NCT07345247
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing a procedure called radiation segmentectomy for adults with liver cancer. Doctors deliver tiny radioactive resin beads directly to the tumor's blood supply to kill cancer cells while sparing healthy tissue. The goal is to find the best radiation dose for complete tumor shrinkage and to confirm the treatment is safe. 150 participants will be followed for at least 3 months after treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Y-90 resin microspheres
- What this could lead to
- If successful, this could establish a standard dose for using resin microspheres in radiation segmentectomy, improving tumor control while minimizing liver damage.
- What could go wrong
- This is a single-center, non-randomized study with 150 participants. Results may not apply to all liver cancer patients, and there are risks of radiation-induced liver injury or incomplete tumor response.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Study population will include the patients who will receive radioembolization for radiation segmentectomy intent for primary or secondary liver tumors
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged ≥18 years * Underwent RE as a RS intent (have single or \<3 tumors in same or neighboring 2 segments) for the treatment of HCC or metastatic tumor to liver. * Presence of extrahepatic disease * Tumor size less than 8 cm * Child Pugh Score \<B9 Exclusion Criteria: * Presence of macrovascular invasion, * Presence of extrahepatic disease, * Cholangiocarcinoma or mixed HCC-cholangiocarcinoma * Not willing to attend follow-up visits.
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
20 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Acibadem Adana Hospital
RECRUITINGAdana, Turkey (Türkiye)
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Acibadem Izmir Hospital
NOT_YET_RECRUITINGIzmir, Turkey (Türkiye)
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Adana City Hospital
NOT_YET_RECRUITINGAdana, Turkey (Türkiye)
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Bilkent City Hospital
NOT_YET_RECRUITINGAnkara, Turkey (Türkiye)
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Cam ve Sakura Education and Reseach Hospital
RECRUITINGIstanbul, Turkey (Türkiye)
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Cukurova University
NOT_YET_RECRUITINGAdana, Turkey (Türkiye)
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Ege University
NOT_YET_RECRUITINGIzmir, Turkey (Türkiye)
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Erciyes University
RECRUITINGKayseri, Turkey (Türkiye)
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Gazi Yasargil Education and Research Hospital
NOT_YET_RECRUITINGDiyarbakır, Turkey (Türkiye)
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Gulhane Education and Research Hospital
NOT_YET_RECRUITINGAnkara, Turkey (Türkiye)
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Hacettepe University
RECRUITINGAnkara, Turkey (Türkiye)
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Inonu University
RECRUITINGMalatya, Turkey (Türkiye)
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Istanbul Unicersity Cerrahpasa Medical School
NOT_YET_RECRUITINGIstanbul, Turkey (Türkiye)
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Istanbul University Capa Medical School
RECRUITINGIstanbul, Turkey (Türkiye)
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Katip Celebi Education and Research Hospital
RECRUITINGIzmir, Turkey (Türkiye)
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Kocaeli University
NOT_YET_RECRUITINGKocaeli, Turkey (Türkiye)
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Konya Selcuk University
RECRUITINGKonya, Turkey (Türkiye)
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Marmara University
RECRUITINGIstanbul, Turkey (Türkiye)
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Mersin City Hospital
NOT_YET_RECRUITINGMersin, Turkey (Türkiye)
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Pamukkale University
NOT_YET_RECRUITINGDenizli, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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