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Large study digs into rare brain tumors to uncover hidden risks

NCT ID NCT03251989

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 31 times

Summary

This completed study enrolled 326 adults with rare central nervous system tumors, such as medulloblastoma and ependymoma. Participants completed surveys about their health, symptoms, and exposures, and provided a saliva sample for genetic analysis. The goal was to better understand what factors are linked to these rare tumors, which could help guide future research into screening or treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Cancer Institute (NCI)/ Neuro-Oncology Branch

    Bethesda, Maryland, 20892, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify genetic or environmental risk factors for rare CNS tumors, potentially pointing toward future screening or treatment targets.

What could go wrong

This is an observational study that only collects self-reported data and saliva samples. It does not test any treatment, so it cannot directly improve outcomes. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

brain cancer central nervous system cancer Choroid Plexus Neoplasms ependymoma glioma grade III meningioma medulloblastoma Neuroectodermal Tumors, Primitive primitive neuroectodermal tumor rhabdoid tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.