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Quick pump upgrade may save hearts in shock

NCT ID NCT07655479

First seen Jun 23, 2026 · Last updated Jun 23, 2026

Summary

This study tests whether rapidly switching from a standard heart pump (Impella CP) to a more powerful one (Impella 5.5) within 24 hours after a heart attack improves outcomes for people in cardiogenic shock. About 115 adults aged 18-77 with severe shock will be enrolled. The goal is to see if this faster escalation reduces the need for strong medications and leads to fewer complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Impella heart pumps (Impella CP and Impella 5.5)

What this could lead to

If successful, this could establish a faster, more effective way to support the heart during cardiogenic shock, potentially reducing complications and improving survival.

What could go wrong

This is an early-stage trial with only 115 participants, so results may not apply to all patients. The procedure carries risks like bleeding or device-related complications.

Conditions

The condition(s) this trial relates to.

Myocardial Infarction Shock, Cardiogenic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.