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Promising combo for tough blood cancers halted early — only 4 patients enrolled

NCT ID NCT00776373

First seen Nov 05, 2025 · Last updated Jun 18, 2026 · Updated 35 times

Summary

This study tested whether adding rapamycin to high-dose chemotherapy could help people with aggressive blood cancers (like certain leukemias and lymphomas) that had returned or not responded to prior treatment. Only 4 adults aged 18–65 took part before the study was stopped early. The goal was to check safety and whether the combination could control the disease, but results are limited due to the small size.

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Contacts and locations

Locations

  • University of Pennsylvania Abramson Cancer Center

    Philadelphia, Pennsylvania, 19066, United States

Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia adult T-cell leukemia/lymphoma blast phase chronic myelogenous leukemia, BCR-ABL1 positive Burkitt lymphoma chronic myelogenous leukemia, BCR-ABL1 positive lymphoblastic lymphoma Precursor Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.