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New imaging method could reduce need for brain tumor biopsies

NCT ID NCT04469244

Knowledge-focused Sponsor: Central Hospital, Nancy, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at whether a special PET scan technique called radiomics can help doctors figure out the type and behavior of brain tumors (gliomas) without needing a surgical biopsy. Researchers analyzed scans from 1000 patients who had already received an 18F-FDOPA PET scan. The goal was to see if computer analysis of the scan images could predict the tumor's molecular features and detect recurrence. If it works, this could offer a non-invasive way to guide treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
18F-FDOPA (a radioactive tracer used in PET scans)
What this could lead to
If successful, this approach could help doctors diagnose and monitor gliomas without invasive biopsies, using only imaging.
What could go wrong
This is a retrospective analysis of existing data, not a treatment trial. The results may not change clinical practice immediately and need further validation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,000 people

The number who actually took part.

Started

Jul 2020

Finished

Oct 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

common population that underwent a PET/CT scan at 18F-FDOPA for its glioma

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient having performed a PET/CT examination at 18F-FDOPA for his glioma in the nuclear medicine department of the CHRU de Brabois for which the raw data are available; * Person who received full information on the organization of the research and did not object to the use of these data; * Patients affiliated to a social security scheme Exclusion Criteria: * \- Person who received full information on the organization of the research and who objected to the use of the data * Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice). * A person of full age who is unable to give consent and who is not subject to a legal protection measure.

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Conditions

The condition(s) this trial relates to.

brain glioma glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Study on the use of radiomics in gliomas of initial disgnosis

Contacts and locations

Locations

  • CHRU of Nancy

    Vandœuvre-lès-Nancy, France, 54511, France