Major trial tests gentler radiation combo for HPV throat cancer

NCT ID NCT01302834

Disease control Sponsor: Radiation Therapy Oncology Group Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times

Summary

This large phase 3 trial studied nearly 1,000 people with HPV-related oropharyngeal cancer to see if replacing chemotherapy with a targeted drug (cetuximab) during radiation could work as well or better. The goal was to find a treatment that controls the disease while possibly reducing side effects. Results help doctors choose the best approach for this specific type of throat cancer.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

987 people

The number who actually took part.

Started

Jun 2011

Finished

Sep 2025

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 120 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Pathologically (histologically or cytologically) proven diagnosis of squamous cell carcinoma (including the histological variants papillary squamous cell carcinoma and basaloid squamous cell carcinoma) of the oropharynx (tonsil, base of tongue, soft palate, or oropharyngeal walls). 2. Patients must be positive for p16, determined by central review prior to randomization. 3. Patients must have clinically or radiographically evident measurable disease at the primary site or at nodal stations. Tonsillectomy or local excision of the primary without removal of nodal disease is permitted, as is excision removing gross nodal disease but with intact primary site. Limited neck dissections retrieving ≤ 4 nodes are permitted and considered as non-therapeutic nodal excisions. Fine needle aspirations of the neck are insufficient due to limited tissue for retrospective central review. Biopsy specimens from the primary or nodes measuring at least 3-5 mm are required. 4. Clinical stage T1-2, N2a-N3 or T3-4, any N (AJCC, 7th ed.; see Appendix III), including no distant metastases, based upon the following minimum diagnostic workup: * General history and physical examination by a radiation oncologist and medical oncologist within 8 weeks prior to registration; * Examination by an ear, nose, and throat (ENT) or head and neck surgeon, including laryngopharyngoscopy (mirror and/or fiberoptic and/or direct procedure) within 8 weeks prior to registration; * One of the following combinations of imaging is required within 8 weeks prior to registration: 1. A computerized tomography (CT) scan of the neck (with contrast) and a chest CT scan (with or without contrast); 2. or a magnetic resonance imaging (MRI) scan of the neck (with contrast) and a chest CT scan (with or without contrast); 3. or a CT scan of neck (with contrast) and a positron emission tomography (PET)/CT of neck and chest (with or without contrast); 4. or an MRI of the neck (with contrast) and a PET/CT of neck and chest (with or without contrast). Note: A CT scan of neck and/or a PET/CT performed for radiation planning and read by a radiologist may serve as both staging and planning tools. 5. Zubrod Performance Status 0-1 within 2 weeks prior to registration 6. Age ≥ 18; 7. Complete blood count (CBC)/differential obtained within 2 weeks prior to registration on study, with adequate bone marrow function, defined as follows: * Absolute neutrophil count (ANC) \> 1,500 cells/mm3; * Platelets \> 100,000 cells/mm3; * Hemoglobin (Hgb) \> 8.0 g/dl; Note: The use of transfusion or other intervention to achieve Hgb \> 8.0 g/dl is acceptable. 8. Adequate hepatic function, defined as follows: * Bilirubin \< 2 mg/dl within 2 weeks prior to registration; * Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) \< 3 x the upper limit of normal within 2 weeks prior to registration; 9. Adequate renal function, defined as follows: • Serum creatinine \< 1.5 mg/dl within 2 weeks prior to registration or creatinine clearance (CCr) ≥ 50 ml/min within 2 weeks prior to registration determined by 24-hour collection or estimated by Cockcroft-Gault formula: CCr male = \[(140 - age) x (wt in kg)\] \[(Serum Cr mg/dl) x (72)\] CCr female = 0.85 x (CCr male) 10. Patients must provide their smoking history (for stratification) via the computer-assisted self interview (CASI) head and neck risk factor survey tool. 11. Negative serum pregnancy test within 2 weeks prior to registration for women of childbearing potential; 12. Women of childbearing potential and male participants must agree to use a medically effective means of birth control throughout their participation in the treatment phase of the study and until at least 60 days following the last study treatment. 13. Patients who are human immunodeficiency virus (HIV) positive but have no prior acquired immune deficiency syndrome (AIDS) -defining illness and have CD4 cells of at least 350/mm3 are eligible. Patient HIV status must be known prior to registration. Patients must not be sero-positive for Hepatitis B (Hepatitis B surface antigen positive or anti-hepatitis B core antigen positive) or sero-positive for Hepatitis C (anti-Hepatitis C antibody positive). However, patients who are immune to hepatitis B (anti-Hepatitis B surface antibody positive) are eligible (e.g. patients immunized against hepatitis B). HIV-positive patients must not have multi-drug resistant HIV infection or other concurrent AIDS-defining conditions. 14. Patient must provide study specific informed consent prior to study entry, including consent for mandatory submission of tissue for required, central p16 review and consent to participate in the computer-assisted self interview (CASI) survey questions regarding smoking history. Exclusion Criteria: 1. Cancers considered to be from an oral cavity site (oral tongue, floor mouth, alveolar ridge, buccal or lip), nasopharynx, hypopharynx, or larynx, even if p16 positive, are excluded. Carcinoma of the neck of unknown primary site origin (even if p16 positive) are excluded from participation. 2. Stage T1-2, N0-1; 3. Distant metastasis or adenopathy below the clavicles; 4. Gross total excision of both primary and nodal disease; this includes tonsillectomy, local excision of primary site, and nodal excision that removes all clinically and radiographically evident disease. 5. Simultaneous primaries or bilateral tumors; 6. Prior invasive malignancy (except non-melanomatous skin cancer) unless disease free for a minimum of 3 years (For example, carcinoma in situ of the breast, oral cavity, or cervix are all permissible); 7. Prior systemic chemotherapy for the study cancer; note that prior chemotherapy for a different cancer is allowable; 8. Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields; 9. Severe, active co-morbidity, defined as follows: * 9.1 Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months; * 9.2 Transmural myocardial infarction within the last 6 months; * 9.3 Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration; * 9.4 Chronic Obstructive Pulmonary Disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy within 30 days of registration; * 9.5 Hepatic insufficiency resulting in clinical jaundice and/or coagulation defects; note, however, that laboratory tests for liver function and coagulation parameters are not required for entry into this protocol. * 9.6 Acquired Immune Deficiency Syndrome (AIDS) based upon current Centers for Disease Control and Prevention (CDC) definition with immune compromise greater than that noted in Section 3.1.13; note, however, that HIV testing is not required for entry into this protocol. The need to exclude patients with AIDS from this protocol is necessary because the treatments involved in this protocol may be significantly immunosuppressive. Protocol-specific requirements may also exclude immuno-compromised patients. 10. Pregnancy or women of childbearing potential and men who are sexually active and not willing/able to use medically acceptable forms of contraception; this exclusion is necessary because the treatment involved in this study may be significantly teratogenic. 11. Prior allergic reaction to cisplatin or cetuximab; 12. Prior cetuximab or other anti-EGFR therapy.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms human papilloma virus infection oropharynx squamous cell carcinoma precancerous condition Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Head and neck cancer Precancerous condition

Contacts and locations

Locations

Study site

Santa Clara, California, 95051, United States
Adams Cancer Center

Gettysburg, Pennsylvania, 17325, United States
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210-1240, United States
Auburn Radiation Oncology

Auburn, California, 95603, United States
Baptist Cancer Institute - Jacksonville

Jacksonville, Florida, 32207, United States
Baptist Medical Center South

Jascksonville, Florida, 32258, United States
Barberton Citizens Hospital

Barberton, Ohio, 44203, United States
Barnes-Jewish West County Hospital

St Louis, Missouri, 63141, United States
Battle Creek Health System Cancer Care Center

Battle Creek, Michigan, 49017, United States
Bay Area Cancer Care Center at Bay Area Medical Center

Marinette, Wisconsin, 54143, United States
Billings Clinic - Downtown

Billings, Montana, 59107-7000, United States
Blumenthal Cancer Center at Carolinas Medical Center

Charlotte, North Carolina, 28232-2861, United States
Boulder Community Hospital

Boulder, Colorado, 80301-9019, United States
Butterworth Hospital at Spectrum Health

Grand Rapids, Michigan, 49503, United States
CCOP - Christiana Care Health Services

Newark, Delaware, 19713, United States
CCOP - Greenville

Greenville, South Carolina, 29615, United States
CCOP - Kansas City

Prairie Village, Kansas, 66208, United States
CCOP - Ochsner

New Orleans, Louisiana, 70121, United States
CCOP - St. Louis-Cape Girardeau

St Louis, Missouri, 63141, United States
CCOP - Virginia Mason Research Center

Seattle, Washington, 98101, United States
Cancer Center at Ball Memorial Hospital

Muncie, Indiana, 47303-3499, United States
Cancer Centers of the Carolinas - Faris Road

Greenville, South Carolina, 29605, United States
Cancer Centers of the Carolinas - Spartanburg

Spartanburg, South Carolina, 29307, United States
Cancer Institute at St. John's Hospital

Springfield, Illinois, 62702, United States
Cancer Institute of Cape Girardeau, LLC

Cape Girardeau, Missouri, 63703, United States
Cancer Institute of New Jersey at Cooper - Voorhees

Voorhees Township, New Jersey, 08043, United States
Cancer Treatment Center

Wooster, Ohio, 44691, United States
CancerCare Manitoba

Winnipeg, Manitoba, R3E 0V9, Canada
Cardinal Bernardin Cancer Center at Loyola University Medical Center

Maywood, Illinois, 60153, United States
Case Comprehensive Cancer Center

Cleveland, Ohio, 44106-5065, United States
Center for Cancer Care at Goshen General Hospital

Goshen, Indiana, 46526, United States
Charles M. Barrett Cancer Center at University Hospital

Cincinnati, Ohio, 45267, United States
Cherry Tree Cancer Center

Hanover, Pennsylvania, 17331, United States
City of Hope Comprehensive Cancer Center

Duarte, California, 91010-3000, United States
Clackamas Radiation Oncology Center

Clackamas, Oregon, 97015, United States
Cleveland Clinic Cancer Center at Fairview Hospital

Cleveland, Ohio, 44111, United States
Cleveland Clinic Taussig Cancer Center

Cleveland, Ohio, 44195, United States
Coastal Cancer Center at Sentara Virginia Beach General Hospital

Virginia Beach, Virginia, 23454, United States
Community Regional Cancer Care at Community Hospital East

Indianapolis, Indiana, 46219, United States
Community Regional Cancer Care at Community Hospital North

Indianapolis, Indiana, 46256, United States
Creticos Cancer Center at Advocate Illinois Masonic Medical Center

Chicago, Illinois, 60657, United States
Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center

Savannah, Georgia, 31403-3089, United States
Dale and Frances Hughes Cancer Center at Pocono Medical Center

East Stroudsburg, Pennsylvania, 18301, United States
David C. Pratt Cancer Center at St. John's Mercy

St Louis, Missouri, 63141, United States
Decatur Memorial Hospital Cancer Care Institute

Decatur, Illinois, 62526, United States
Dubs Cancer Center at Rogue Valley Medical Center

Medford, Oregon, 97504, United States
Edwards Comprehensive Cancer Center at Cabell Huntington Hospital

Huntington, West Virginia, 25701, United States
Elkhart General Hospital

Elkhart, Indiana, 46515, United States
Enloe Cancer Center at Enloe Medical Center

Chico, California, 95926, United States
Evanston Hospital

Evanston, Illinois, 60201-1781, United States
Fairview Southdale Hospital

Edina, Minnesota, 55435, United States
FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center

Pinehurst, North Carolina, 28374, United States
Flagler Cancer Center

Saint Augustine, Florida, 32086, United States
Florida Cancer Center - Palatka

Palatka, Florida, 32177, United States
Florida Hospital Cancer Institute at Florida Hospital Orlando

Orlando, Florida, 32803-1273, United States
Flower Hospital Cancer Center

Sylvania, Ohio, 43560, United States
Fox Chase Cancer Center - Philadelphia

Philadelphia, Pennsylvania, 19111-2497, United States
Frederick R. and Betty M. Smith Cancer Treatment Center

Sparta, New Jersey, 07871, United States
Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States
George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus

New Britain, Connecticut, 06050, United States
Georgia Cancer Center for Excellence at Grady Memorial Hospital

Atlanta, Georgia, 30303, United States
Gibbs Regional Cancer Center at Spartanburg Regional Medical Center

Spartanburg, South Carolina, 29303, United States
Greenebaum Cancer Center at University of Maryland Medical Center

Baltimore, Maryland, 21201, United States
Gundersen Lutheran Center for Cancer and Blood

La Crosse, Wisconsin, 54601, United States
H. Lee Moffitt Cancer Center and Research Institute at University of South Florida

Tampa, Florida, 33612-9497, United States
Highland Hospital of Rochester

Rochester, New York, 14620, United States
Hillcrest Cancer Center at Hillcrest Hospital

Mayfield Heights, Ohio, 44124, United States
Hollings Cancer Center at Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Hudner Oncology Center at Saint Anne's Hospital - Fall River

Fall River, Massachusetts, 02721, United States
Hulston Cancer Center at Cox Medical Center South

Springfield, Missouri, 65807, United States
Huntsman Cancer Institute at University of Utah

Salt Lake City, Utah, 84112, United States
Integrated Community Oncology Network

Jacksonville Beach, Florida, 32250, United States
Integrated Community Oncology Network - Orange Park

Orange Park, Florida, 32073, United States
Integrated Community Oncology Network at Southside Cancer Center

Jacksonville, Florida, 32207, United States
James Graham Brown Cancer Center at University of Louisville

Louisville, Kentucky, 40202, United States
James P. Wilmot Cancer Center at University of Rochester Medical Center

Rochester, New York, 14642, United States
John H. Stroger, Jr. Hospital of Cook County

Chicago, Illinois, 60612-3785, United States
John Stoddard Cancer Center at Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center

Murray, Utah, 84157, United States
Josephine Ford Cancer Center at Henry Ford Hospital

Detroit, Michigan, 48202, United States
Kaiser Permanente - Division of Research - Oakland

Oakland, California, 94611, United States
Kaiser Permanente Medical Center - South San Francisco

South San Francisco, California, 94080, United States
Kansas City Cancer Centers - North

Kansas City, Missouri, 64154, United States
Kansas City Cancer Centers - South

Kansas City, Missouri, 64131, United States
Kansas City Cancer Centers - Southwest

Overland Park, Kansas, 66210, United States
Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center

Kansas City, Kansas, 66160-7357, United States
Kingsbury Center for Cancer Care at Cheshire Medical Center

Keene, New Hampshire, 03431, United States
Kinston Medical Specialists

Kinston, North Carolina, 28501, United States
Knight Cancer Institute at Oregon Health and Science University

Portland, Oregon, 97239-3098, United States
Lacks Cancer Center at Saint Mary's Health Care

Grand Rapids, Michigan, 49503, United States
Lahey Clinic Medical Center - Burlington

Burlington, Massachusetts, 01805, United States
Lake/University Ireland Cancer Center

Mentor, Ohio, 44060, United States
Lourdes Regional Cancer Center

Binghamton, New York, 13905, United States
Lucille P. Markey Cancer Center at University of Kentucky

Lexington, Kentucky, 40536-0093, United States
M. D. Anderson Cancer Center at University of Texas

Houston, Texas, 77030-4009, United States
M.D. Anderson Cancer Center at Orlando

Orlando, Florida, 32806, United States
Maine Center for Cancer Medicine and Blood Disorders - Scarborough

Scarborough, Maine, 04074, United States
Mary Bird Perkins Cancer Center - Baton Rouge

Baton Rouge, Louisiana, 70809, United States
McFarland Clinic, PC

Ames, Iowa, 50010, United States
McGill Cancer Centre at McGill University

Montreal, Quebec, H2W 1S6, Canada
McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center

Reading, Pennsylvania, 19612-6052, United States
McKee Medical Center

Loveland, Colorado, 80539, United States
Medical College of Wisconsin Cancer Center

Milwaukee, Wisconsin, 53226, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Mercy Cancer Center at Mercy San Juan Medical Center

Carmichael, California, 95608, United States
Mercy General Hospital

Sacramento, California, 95819, United States
Mercy and Unity Cancer Center at Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy and Unity Cancer Center at Unity Hospital

Fridley, Minnesota, 55432, United States
Methodist Estabrook Cancer Center

Omaha, Nebraska, 68114, United States
Michiana Hematology-Oncology, PC - South Bend

Mishawaka, Indiana, 46545-1470, United States
Mission Hospitals - Memorial Campus

Asheville, North Carolina, 28801, United States
Monmouth Medical Center

Long Branch, New Jersey, 07740-6395, United States
Moses Cone Regional Cancer Center at Wesley Long Community Hospital

Greensboro, North Carolina, 27403-1198, United States
NSMC Cancer Center - Peabody

Danvers, Massachusetts, 01923, United States
Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler

Savannah, Georgia, 31405, United States
Natalie Warren Bryant Cancer Center at St. Francis Hospital

Tulsa, Oklahoma, 74136, United States
Nebraska Medical Center

Omaha, Nebraska, 68198, United States
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, 03756-0002, United States
North Broward Medical Center

Dearfield Beach, Florida, 33064-3596, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital

Yakima, Washington, 98902, United States
North Suburban Medical Center

Thornton, Colorado, 80229, United States
Northeast Georgia Medical Center

Gainesville, Georgia, 30501, United States
Northwest Cancer Specialists at Vancouver Cancer Center

Vancouver, Washington, 98684, United States
Northwest Community Hospital

Arlington Heights, Illinois, 60005, United States
Northwest Ohio Oncology Center

Maumee, Ohio, 43537-1839, United States
Oklahoma University Cancer Institute

Oklahoma City, Oklahoma, 73104, United States
Park Nicollet Cancer Center

Saint Louis Park, Minnesota, 55416, United States
Parkview Regional Cancer Center at Parkview Health

Fort Wayne, Indiana, 46805, United States
Payson Center for Cancer Care at Concord Hospital

Concord, New Hampshire, 03301, United States
Penrose Cancer Center at Penrose Hospital

Colorado Springs, Colorado, 80933, United States
Porter Adventist Hospital

Denver, Colorado, 80210, United States
Precision Radiotherapy at University Pointe

West Chester, Ohio, 45069, United States
Providence Cancer Center

Anchorage, Alaska, 99508, United States
Providence Cancer Center at PMCC

Medford, Oregon, 97504, United States
Providence Cancer Center at Providence Portland Medical Center

Portland, Oregon, 97213-2967, United States
Providence St. Vincent Medical Center

Portland, Oregon, 97225, United States
Radiation Oncology Center - Roseville

Roseville, California, 95661, United States
Radiation Oncology Centers - Cameron Park

Cameron Park, California, 95682, United States
Radiological Associates of Sacramento Medical Group, Incorporated

Sacramento, California, 95815, United States
Rapid City Regional Hospital

Rapid City, South Dakota, 57701, United States
Rebecca and John Moores UCSD Cancer Center

La Jolla, California, 92093-0658, United States
Regional Cancer Center at Memorial Medical Center

Springfield, Illinois, 62781-0001, United States
Regional Cancer Center at Singing River Hospital

Pascagoula, Mississippi, 39581, United States
Regions Hospital Cancer Care Center

Saint Paul, Minnesota, 55101, United States
Renown Institute for Cancer at Renown Regional Medical Center

Reno, Nevada, 89502, United States
Robert H. Lurie Comprehensive Cancer Center at Northwestern University

Chicago, Illinois, 60611-3013, United States
Rocky Mountain Cancer Centers - Aurora

Aurora, Colorado, 80012, United States
Rohnert Park Cancer Center

Rohnert Park, California, 94928, United States
Rosenfeld Cancer Center at Abington Memorial Hospital

Abington, Pennsylvania, 19001, United States
Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center

Burbank, California, 91505, United States
Sacred Heart Cancer Center at Sacred Heart Hospital

Pensacola, Florida, 32504, United States
Saint Joseph Mercy Cancer Center

Ann Arbor, Michigan, 48106-0995, United States
Schiffler Cancer Center at Wheeling Hospital

Wheeling, West Virginia, 26003, United States
Seacoast Cancer Center at Wentworth - Douglass Hospital

Dover, New Hampshire, 03820, United States
Sentara Cancer Institute at Sentara Norfolk General Hospital

Norfolk, Virginia, 23507, United States
Siouxland Hematology-Oncology Associates, LLP

Sioux City, Iowa, 51101, United States
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis

St Louis, Missouri, 63110, United States
Solano Radiation Oncology Center

Vacaville, California, 95687, United States
Southwest General Health Center

Middleburg Heights, Ohio, 44130, United States
St. Agnes Hospital Cancer Center

Baltimore, Maryland, 21229, United States
St. Anne Mercy Hospital

Toledo, Ohio, 43623, United States
St. Charles Mercy Hospital

Oregon, Ohio, 43616, United States
St. Francis Hospital and Health Centers - Beech Grove Campus

Beech Grove, Indiana, 46107, United States
St. Joseph Cancer Center

Bellingham, Washington, 98225, United States
St. Mary Regional Cancer Center

Langhorne, Pennsylvania, 19047, United States
St. Mary's Hospital Medical Center - Green Bay

Green Bay, Wisconsin, 54303, United States
St. Vincent Hospital Regional Cancer Center

Green Bay, Wisconsin, 54307-3508, United States
Summa Center for Cancer Care at Akron City Hospital

Akron, Ohio, 44309-2090, United States
Swedish Medical Center

Englewood, Colorado, 80110, United States
Theda Care Cancer Institute

Appleton, Wisconsin, 54911, United States
UCSF Helen Diller Family Comprehensive Cancer Center

San Francisco, California, 94115, United States
UHHS Westlake Medical Center

Westlake, Ohio, 44145, United States
University of Chicago Cancer Research Center

Chicago, Illinois, 60637-1470, United States
University of Miami Sylvester Comprehensive Cancer Center - Miami

Miami, Florida, 33136, United States
University of New Mexico Cancer Center

Albuquerque, New Mexico, 87131-5636, United States
University of Texas Medical Branch

Galveston, Texas, 77555-0361, United States
University of Wisconcin Cancer Center at Aspirus Wausau Hospital

Wausau, Wisconsin, 54401, United States
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center

Madison, Wisconsin, 53792-6164, United States
Utah Cancer Specialists at UCS Cancer Center

Salt Lake City, Utah, 84106, United States
Utah Valley Regional Medical Center - Provo

Provo, Utah, 84604, United States
Val and Ann Browning Cancer Center at McKay-Dee Hospital Center

Ogden, Utah, 84403, United States
Vanderbilt-Ingram Cancer Center

Nashville, Tennessee, 37232-6838, United States
Veterans Affairs Medical Center - Milwaukee

Milwaukee, Wisconsin, 53295, United States
Winship Cancer Institute of Emory University

Atlanta, Georgia, 30322, United States
York Cancer Center at Apple Hill Medical Center

York, Pennsylvania, 17405, United States

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