Smartwatches could read Parkinson's quality of life
NCT ID NCT06209502
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This observational study explores whether data from everyday smartwatches and smartphones can be used to remotely assess the health-related quality of life of people with Parkinson's disease. Researchers will develop an algorithm, called the Q-index, based on passively collected data from these devices. The study includes 95 participants with Parkinson's disease at various stages, aiming to see if this approach can monitor quality of life without frequent clinic visits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Wearable and portable devices (smartwatch and smartphone) with the Koios Care app
- What this could lead to
- If successful, this could enable remote, passive monitoring of quality of life in Parkinson's patients, potentially improving care and reducing clinic visits.
- What could go wrong
- This is an early proof-of-concept study with a small number of participants. The algorithm may not be accurate enough for clinical use, and results may not generalize to all Parkinson's patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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95 people
The number who actually took part.
- Started
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Nov 2023
- Finished
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Aug 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The recruitment process for Parkinson's Disease patients begins during a consultation taking place in one of the three participating clinics. Specifically, a member of the medical team informs the patient about the ongoing study, including but not limited to, its goals, the technology, and the timeline of the study. The recruitment of a Parkinson's Disease patient also appears as an opportunity to recruit healthy participants. Specifically, the study targets members of the close circle of the patient, i.e., age-matched friends and close family members. It should be noted that to avoid recruitment bias (e.g., the partner of the patient stays home to support their patient partner), the partner of the patient is left as the emergency (low recruitment rate for healthy controls) recruitment scenario. In addition, the recruitment procedure for healthy controls will be supported by wall posters in the hospital campus and web advertising.
- Ages
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30 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Males and females between the ages of 30 and 75 * Agree to download and install the Koios Care application to their personal Android smartphone. * People diagnosed with idiopathic PD based on the MDS-PD criteria. The diagnosis must be confirmed by bradykinesia plus one of the other cardinal signs (resting tremor, rigidity or postural instability not caused by primary visual, vestibular, cerebellar, or proprioceptive dysfunction) being present, without any other known or suspected cause of Parkinson's Disease. o PD patients that are under the effects of a Deep Brain Stimulation (DBS) device or a levodopa pump (duodopa or lecigimon). Given that all other conditions are also met. * Score between one-and-a-half (1.5) and three (3) at the H\&Y rating scale in the "ON" state (population A) * Score of one (1) at the H\&Y rating scale in the "ON" state (population B) Exclusion Criteria: * The candidate cannot speak or comprehend the French/Dutch (depending on the clinical site s/he belongs to) language at a sufficient level. * The reluctance of the candidate or her/his inability to provide written consent (e.g., due to mental health problems or severe physical disabilities). * The candidate is not an Android smartphone owner and user for at least six (6) months. * The candidate's Android smartphone is not compatible with the Koios Care application. * The candidate suffers from dementia as judged by the investigator. For this we will use MMSE score with a cut-off value ≥ 24. * The candidate has exhibited uncontrolled/extreme measures of depression as judged by the expert investigator, e.g., self-harm, suicide attempts or patient admitted to the hospital for a similar reason. \-- If the participant develops such behavior or s/he is admitted to the hospital for the above reasons during the study, then the candidate is immediately removed from the study. * Any Parkinson's disease-related feature or symptom that could interfere with the study conduct and results as assessed by the investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AZ Delta, Department of Neurology, EC reference 23045
Roeselare, 8800, Belgium
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AZ Oostende, Department of Neurology, EC reference OG-057
Ostend, Belgium
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CHU Charleroi, Department of Neurology, EC reference AH/SG-2023-037
Charleroi, Belgium
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CHU de Liege, Department of Neurology, EC reference 2023/173
Liège, Belgium
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