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New Slow-Release pyridostigmine pill tested for easier dosing

NCT ID NCT07154095

First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 30 times

Summary

This study tested a new sustained-release (slow-release) tablet of pyridostigmine, a drug used to treat myasthenia gravis, against the standard immediate-release tablet. Forty healthy Chinese volunteers took both versions in random order, separated by a washout period. Researchers measured drug levels in the blood and monitored safety. The goal was to see if the new tablet provides a more convenient dosing option.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • West China Second University Hospital

    Chengdu, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pyridostigmine

What this could lead to

If successful, this could lead to a once-daily version of pyridostigmine that is easier for people with myasthenia gravis to take, with fewer doses needed each day.

What could go wrong

This is a very early Phase 1 study in only 40 healthy people, not patients. It only checks drug levels and safety, not whether the new tablet actually improves symptoms.

Conditions

The condition(s) this trial relates to.

myasthenia gravis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.