Gum health linked to skin disease severity in new study
NCT ID NCT07384221
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how the severity of pemphigus vulgaris, a chronic autoimmune skin disease, relates to gum health. Researchers will examine 20 adults with confirmed PV, measuring mouth sores and gum pocket depth, and comparing these with blood antibody levels. The goal is to understand the connection between disease activity and periodontal status.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal how pemphigus vulgaris affects gum health, guiding better dental care for patients.
- What could go wrong
- This is a small observational study with only 20 participants, so results may not apply to everyone. It does not test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Nov 2025
- Expected to finish
-
Feb 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of adult patients diagnosed with Pemphigus Vulgaris who are receiving treatment or follow-up at the dermatology clinic.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18 years and older. * Clinically and histopathologically confirmed diagnosis of Pemphigus Vulgaris. * Presence of at least 10 natural teeth. * Willingness to participate and signed informed consent. Exclusion Criteria: * Pregnancy or lactation. * Use of systemic antibiotics or anti-inflammatory drugs within the last 3 months. * Periodontal treatment received within the last 6 months.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Pemphigus vulgaris (PV) are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
University of Health Sciences, Gulhane Faculty of Dentistry, Department of Periodontology
RECRUITINGAnkara, 06010, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a melatonin gel help gums heal after deep cleaning?
- Braces vs. clear aligners: which is gentler on your gums?
- Can a laser boost the benefits of deep gum cleaning?
- Nature's mouthwash: could tea tree oil and thyme tame gum disease?
- Gel boosts gum healing after deep cleaning for advanced periodontitis — trial puts it to the test
- Retainer type may shape gum bacteria in ways that matter for oral health