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Eye muscle measurements may flag risky cataract surgeries

NCT ID NCT07517094

Knowledge-focused Sponsor: University Hospital Olomouc Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 30 men taking alpha-blocker drugs for urinary symptoms who were scheduled for cataract surgery. Researchers used a special eye scan to measure the thickness of iris muscles and pupil size. The goal was to see if these measurements could predict intraoperative floppy iris syndrome, a complication that can make cataract surgery more difficult.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help surgeons identify patients at higher risk for floppy iris syndrome before cataract surgery, allowing better preparation.
What could go wrong
This is a small, completed observational study with only 30 participants. The findings may not apply to all patients or reliably predict complications in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

30 people

The number who actually took part.

Started

Jan 2022

Finished

May 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients will be recruited from patients examined before cataract surgery at the Department of Ophthalmology of University Hospital Olomouc.

Ages

18 years and older

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age related cataract * Age over 18 years * Men with diagnosed lower urinary tract symptoms * History of having taken any systemic α1-adrenergic receptor antagonists for lower urinary tract symptoms * Signed informed consent * Performing of pre-operative examination before cataract surgery (best-corrected visual acuity, measurement of refraction, slit lamp and biometric examination) * Measurement on anterior segment optical coherence tomography under photopic (\>300 lux) and scotopic conditions (0 lux) Exclusion Criteria: * Congenital or secondary changes in iris morphology - perforating or blunt eye injuries * Previous uveitis * LIRE performer * History of acute ange-closure glaucoma * Pigment dispersion syndrome * Pseudoexfoliation syndrome * Iris tumors * Previous intraocular surgery * History of use of miotics, mydriatics and α1-adrenergic agonists

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Conditions

The condition(s) this trial relates to.

benign prostatic hyperplasia cataract intraoperative floppy iris syndrome Lower Urinary Tract Symptoms senile cataract

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adrenergic receptor antagonist adverse reaction Age-related cataract Cataract Intraoperative floppy iris syndrome

Contacts and locations

Locations

  • Department of Ophthalmology, University Hospital Olomouc, Olomouc

    Olomouc, 77900, Czechia

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