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Dentists test two ways to save teeth with deep cavities

NCT ID NCT07300124

Disease control Sponsor: Postgraduate Institute of Dental Sciences Rohtak Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two dental treatments for teeth with deep cavities and reversible pulpitis (early nerve inflammation). One treatment caps the exposed nerve directly, while the other removes a small part of the nerve before capping. The study will include 138 people aged 15-40 and follow them for one year to see which approach has a higher success rate and causes less pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dental procedure (direct pulp capping or partial pulpotomy)
What this could lead to
If successful, this study could show which dental procedure is more effective for saving teeth with deep cavities and reversible pulpitis, helping dentists choose the best treatment.
What could go wrong
This is a small, early-stage trial (138 people) that hasn't started recruiting yet. Results may not apply to all patients, and some teeth may still fail despite treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 138 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2025

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients aged 15-40 years. 2. Mature permanent mandibular molars with extremely deep caries on radiograph, giving positive response to pulp sensibility test. 3. Pulpal bleeding can be controlled within 10 minutes 4. Patients having normal periapical status with periapical index (PAI) score ≤ 2 5. Periodontally healthy teeth 6. Positive response to pulp sensibility test Exclusion Criteria: 1. Non restorable teeth 2. Negative response to vitality testing 3. Presence of sinus tract or soft tissue swelling 4. Absence of deep carious lesions radiographically 5. Radiographic signs of internal or external root resorption 6. Patient had moderate to severe pain, but preferred root canal treatment 7. Presence of sound dentin over pulp and pulp not exposed intraoperatively 8. Pulp haemorrhage could not be arrested within 10 minutes. 9. Necrotic pulp evident upon exposure 10. Pregnant women 11. Absence of antagonist teeth 12. Intake of antibiotics in last 30 days

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Conditions

The condition(s) this trial relates to.

dental caries dentin caries pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Extremely deep caries Reversible pulpitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • PGIDS Rohtak

    Rohtak, Haryana, 124001, India

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