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Teen PTSD brain scans reveal memory and emotion links

NCT ID NCT02510755

Knowledge-focused Sponsor: University Hospital, Caen Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how psychological trauma affects memory and brain function in teenagers with post-traumatic stress disorder (PTSD). Researchers used MRI scans to compare brain activity in 19 adolescents with PTSD and healthy teens. The goal was to understand the brain areas involved in emotional memory, which could help improve diagnosis and monitoring of PTSD in young people.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors better understand and diagnose PTSD in teenagers, leading to improved monitoring and support.
What could go wrong
This is a small, early-stage observational study with only 19 participants. It does not test any treatment, so it may not directly lead to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

19 people

The number who actually took part.

Start date

May 2012

Finished

Apr 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

13 to 18 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subjects aged 13-18 years * Informed consent signed by the legal representative and adolescents (e) itself. * Speaking French as their mother tongue * patients:subjects with a history of psychological trauma (eg, accidents of public roads (without head trauma), physical or sexual violence) recruited in the care services of hospitals, the diagnosis of chronic PTSD is made using a standardized interview (SCID). * Healthy controls : subjects who do not have a history of psychological trauma, nor PTSD Exclusion Criteria: * ASD, schizophrenia, ADHD * Head injury with loss of consciousness * Regular or recent use of alcohol or drugs * chronic neurological or endocrine disorder * use of medication that could interfere with the mnemonic or metabolic measurements (psychotropic, hypnotics, anxiolytics, neuroleptics, benzodiazepines, drugs, antiepileptics anti-inflammatory, anti-histamines, central analgesics and muscle relaxants) * Contraindications to MRI (claustrophobia, metallic object intracorporal) * Manual Predominance left * Severe mental retardation evaluated using two subtests from the WISC-IV scales and WAIS III * Reading Disorders valued using the read speed test

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stress disorders, post-traumatic

Contacts and locations

Locations

  • Service de Pédopsychiatrie

    Caen, 14000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.