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Can therapy be tailored to the person? a study seeks answers

NCT ID NCT04106713

Knowledge-focused Sponsor: Institute of Mental Health, Singapore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study looks at how people with depression or anxiety respond to different types of psychotherapy—individual sessions or an online program. It aims to find clues that predict who benefits most from each approach. By understanding these factors, doctors may better match patients to the right therapy, improving outcomes and making care more personal.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Individual psychotherapy and internet-delivered cognitive behavioural therapy (iCBT)
What this could lead to
If successful, this could help match patients to the most effective therapy format, improving personalized mental health care.
What could go wrong
The study is observational and exploratory, so it may not identify clear predictors. Results may not apply beyond this hospital setting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2019

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. For patients: 1. 18-99 years old; 2. have current or past symptoms of anxiety and/or depression; 3. able to communicate and read in English; 4. able to provide informed consent. 5. Waitlist arm: \- Referred for psychotherapy but given a waiting time of 8 weeks or more to the first visit or not assigned to therapy at IMH. 6. Treatment as usual: \- Not assigned to any psychotherapeutic interventions. 7. iCBT: - Referred for iCBT; \- Identified as a 'P2' patient/appropriate for iCBT by triage. 8. Group therapy: \- Referred for group therapy; \- Identified as a 'P2' patient/appropriate for group therapy by triage. 9. Individual psychotherapy: * Referred for individual therapy; * Patient and therapist committed to frequent therapy (ideally fortnightly). 2. For therapists: 1. Therapists who will see OR have been assigned to clients in the waitlist arm, iCBT, group therapy (e.g. PsychUp), and individual psychotherapy group. Exclusion Criteria: 1\. For patients: 1. current active suicidal intention or plan; 2. cognitively-impaired/are unable to consent/lack capacity to consent.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety disorders Depression

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Institute of Mental Health, Singapore

    RECRUITING

    Singapore, Singapore, 539747, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.