Engineered immune cells take aim at two cancer targets
NCT ID NCT05437341
First seen Jun 23, 2026 · Last updated Jun 23, 2026
Summary
This trial tests a new treatment using a patient's own immune cells, engineered to recognize and attack cancer cells that have two specific markers (PSMA and CD70). The study involves 60 patients with advanced cancers that have not responded to standard therapy. The goal is to see if this approach is safe and can shrink tumors.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shenzhen Geno-immune Medical Institute
RECRUITINGShenzhen, Guangdong, 518000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PSMA/CD70 bi-specific CAR-T cells
What this could lead to
If successful, this could provide a new treatment option for patients with certain advanced cancers that express PSMA or CD70.
What could go wrong
This is an early-phase trial (Phase 1/2) with only 60 participants, so safety and effectiveness are not yet proven. CAR-T therapy can cause severe side effects like cytokine release syndrome.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.