Magic mushroom therapy could lift depression in cancer survivors
NCT ID NCT06801041
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 33 times
Summary
This study tests whether psilocybin, the active ingredient in magic mushrooms, combined with talk therapy can safely help cancer survivors who feel depressed or anxious. Twenty adults who have finished cancer treatment and have no brain tumors will receive a single dose of psilocybin in an outpatient setting. Researchers will track side effects and mood changes to see if this approach is feasible and worth studying further.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The University of Texas M. D. Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
psilocybin
What this could lead to
If it works, this could point toward a new way to ease depression and anxiety in cancer survivors, offering relief without long-term medication.
What could go wrong
This is a small, early-phase trial with only 20 participants, so results may not apply to everyone. Psilocybin can cause temporary psychological distress or side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.