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Could a 'Blood Injection' boost sexual pleasure? new trial investigates

NCT ID NCT05769283

Symptom relief Sponsor: Medstar Health Research Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a one-time injection of platelet-rich plasma (PRP) into the vaginal wall and around the clitoris can improve sexual function and satisfaction in sexually active women. Fifty-two women received either the PRP injection or a placebo (saline) injection and completed questionnaires about their sexual experience before and after treatment. The goal was to see if this simple, natural approach could enhance desire, arousal, lubrication, orgasm, satisfaction, and reduce pain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Platelet-rich plasma (PRP) — a solution made from a person's own blood, rich in platelets, injected into the vaginal wall and around the clitoris
What this could lead to
If it works, this could offer a non-hormonal, natural option to improve sexual satisfaction in women.
What could go wrong
This is a small, early-stage trial with only 52 participants. The placebo effect is strong in sexual function studies, and results may not apply to all women.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

52 people

The number who actually took part.

Started

Aug 2023

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Menarchal women (assigned female at birth) * Age ≥ 18 years of age and \<51 · Sexually active with at least one episode of sexual activity per week defined as follows: * Partnered or solo penetrative or non-penetrative stimulation of the clitoris or vagina * English-speaking * Willingness and ability to comply with the study requirements Exclusion Criteria: * Pregnancy * Pelvic organ prolapse (defined as symptomatic prolapse protruding beyond the hymen) * History of prior vaginal mesh or midurethral mesh sling surgery * History of pelvic radiation * History of or diagnosis of chronic pelvic pain * History of female genital mutilation * History of prolapse or incontinence surgery * History of genital tract malignancy

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Conditions

The condition(s) this trial relates to.

Sexual Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sexual activity Sexual behavior

Contacts and locations

Locations

  • MedStar Lafayette Center

    Washington D.C., District of Columbia, 20036, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.