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Can your own blood ease knee arthritis pain?

NCT ID NCT07558980

Knowledge-focused Sponsor: Iuliu Hatieganu University of Medicine and Pharmacy Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at 40 people with knee osteoarthritis who received injections of platelet-rich plasma (PRP) made from their own blood. Researchers measured pain, function, and inflammation markers to see how PRP might help. The goal was to better understand the treatment's effects, not to prove it works for everyone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
platelet-rich plasma (PRP)
What this could lead to
If successful, this could help doctors understand how PRP works for knee arthritis and guide better treatment plans.
What could go wrong
This is a small, observational study with no control group, so results may not prove PRP is effective. It only looks at short-term effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Oct 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 40 and 80 years 2. Diagnosis of unilateral or bilateral gonarthrosis radiological grade 2-3 Kellgren-Lawrence 3. Knee joint pain greater than 4 on the VAS scale 4. History of knee joint pain for at least 6 months 5. Patients who are to receive an inpatient PRP injection Exclusion Criteria: 1. Diagnosis of secondary gonarthrosis 2. History of inflammatory rheumatological disease or gout 3. History of recent minor (1 month) or major (2 years) trauma to the knee joint 4. History of knee surgery or arthroscopy 5. Infiltrations, physiotherapy or other knee treatments in the last 3 months 6. Diagnosis of neoplasia, hematological or immunological diseases 7. Clinical or biological signs of acute infection 8. Coagulation disorders

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee arthritis osteoarthritis

Contacts and locations

Locations

  • " Iuliu Hatieganu" University of medicine and Pharmacy

    Cluj-Napoca, Cluj, 400347, Romania

More trials for these conditions

Other studies related to the condition(s) this trial covers.