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Cure My Disease

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Massive new registry tracks Kids' radiation to find safer treatments

NCT ID NCT01696721

Knowledge-focused Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is creating a large database of up to 5,000 children who received radiation therapy for cancer. Researchers want to see if proton beam therapy causes fewer long-term side effects than standard photon radiation. By collecting routine medical information, the registry will help doctors understand which type of radiation works best and is safest for children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 5,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2012

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Pediatric patients age \<22 treated with radiation therapy

Ages

Up to 21 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Eligibility Criteria: 1. Patients treated with radiation therapy at one of the participating centers 2. Age \< 22 at time of treatment start. 3. Patients may be enrolled regardless of previous local or systemic treatments received prior to enrollment in the PPCR. 4. Patients may be enrolled regardless of other current local or systemic treatments or disease extent. 5. Patients may be enrolled on the PPCR concurrently with another study or clinical trial.

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Get notified about this study

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pediatric patients treated with radiation therapy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    25 sites in 3 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • California Protons Cancer Therapy Center

    RECRUITING

    San Diego, California, 92121, United States

  • Cincinnati Children's Proton Therapy Center

    RECRUITING

    Liberty Township, Ohio, 45044, United States

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30308, United States

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Maryland Proton Treatment Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

  • New York Proton Center

    RECRUITING

    New York, New York, 10035, United States

  • Northwestern Medicine Chicago Proton Center

    RECRUITING

    Warrenville, Illinois, 60555, United States

  • Oklahoma Proton Center

    RECRUITING

    Oklahoma City, Oklahoma, 73142, United States

  • ProCure Proton Therapy Center- New Jersey

    RECRUITING

    Somerset, New Jersey, 08873, United States

  • ProCure Proton Therapy Center- Oklahoma

    RECRUITING

    Oklahoma City, Oklahoma, 73142, United States

  • Provision Center for Proton Therapy

    ACTIVE_NOT_RECRUITING

    Knoxville, Tennessee, 37909, United States

  • Royal Adelaide Hospital

    RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Stanford University

    RECRUITING

    Palo Alto, California, 94304, United States

  • State University of New York Upstate Medical Center

    RECRUITING

    Syracuse, New York, 13210, United States

  • Texas Center for Proton Therapy

    RECRUITING

    Irving, Texas, 75063, United States

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

  • University Health Network - Princess Margaret Hospital

    RECRUITING

    Toronto, Ontario, M5G 2C1, Canada

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

  • University of Florida Health Proton Therapy Institute

    RECRUITING

    Jacksonville, Florida, 32206, United States

  • University of North Carolina

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • University of Pennsylvania - Roberts Proton Therapy Center

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

  • University of Washington- Seattle Cancer Care Alliance

    RECRUITING

    Seattle, Washington, 98109, United States

  • Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States