MRI scans may reveal hidden clues to premature ejaculation
NCT ID NCT07614854
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study will examine whether the size and shape of the prostatic urethra and seminal vesicles, as seen on prostate MRI, are linked to premature ejaculation (PE) severity. Researchers will compare 150 men with and without PE, all already scheduled for an MRI. Participants will fill out questionnaires and provide a blood sample. The goal is to identify anatomical features that may contribute to PE, which could inform future research.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors understand whether physical features of the prostate and seminal vesicles contribute to premature ejaculation, potentially guiding future treatments.
- What could go wrong
- This is an early observational study, not a treatment trial. It only looks for associations, so it cannot prove cause and effect. Results may not lead to any direct changes in care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
* Any major psychiatric or somatic disorder * Hormonal disorders such as hypothyroidism or hyperthyroidism * Erectile dysfunction (IIEF-15 erectile function domain score \<26) * Age below 18 or above 55 years
- Ages
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18 to 55 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * \- Male aged 18 to 55 years * In a stable, heterosexual, monogamous relationship with the same female partner for at least 6 months * Normal erectile function defined as IIEF-15 erectile function domain score ≥26 * Scheduled for clinically indicated multiparametric prostate MRI due to elevated PSA or hematospermia * Not using any medication that may affect sexual function or psychological status (e.g., SSRIs, PDE5 inhibitors) Exclusion Criteria: * Any major psychiatric or somatic disorder * Hormonal disorders such as hypothyroidism or hyperthyroidism * Erectile dysfunction (IIEF-15 erectile function domain score \<26) * Age below 18 or above 55 years
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Başakşehir Çam and Sakura City Hospital, Department of Urology
Istanbul, Istanbul, 34200, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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- Depression's hidden toll on male sexual function revealed
- New prostate surgery technique may protect ejaculation