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Gene test plus MRI may spot lethal prostate cancer

NCT ID NCT06398639

First seen Nov 10, 2025 · Last updated May 25, 2026 · Updated 25 times

Summary

This study is testing a new way to screen for prostate cancer that is more likely to be life-threatening. It combines a man's genetic risk score with a special MRI scan to find higher-grade cancers. About 1,500 men aged 40-69 with no prior prostate cancer will get a PSA test, an MRI, and genetic testing. The goal is to see if this approach can better identify dangerous cancers and help decide at what age MRI screening is most useful.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02155, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Howard University Hospital

    NOT_YET_RECRUITING

    Washington D.C., District of Columbia, 20060, United States

    Contact

    Contact

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Cancer Institute

    NOT_YET_RECRUITING

    Bethesda, Maryland, 20814, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Walter Reed National Military Medical Center

    NOT_YET_RECRUITING

    Bethesda, Maryland, 20814, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.