5,000 men with advanced prostate cancer to be tracked in new registry study
NCT ID NCT06835218
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is a registry that will follow about 5,000 men with prostate cancer that has come back or spread. It aims to record which treatments doctors actually use in routine care and how the disease progresses over time. Participants are grouped by their cancer stage, from PSA recurrence to metastatic castration-resistant disease. No new treatment is given; the study simply observes and collects data to improve future care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Dec 2032
An estimate. End dates often move.
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult prostate cancer patients (age ≥18 years) who will receive a new line of systemic therapy at the time of study entry or up to 4 weeks thereafter.
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult prostate cancer patients (age ≥18 years). * Diagnosis at time of study inclusion Cohort 1: biochemical recurrence (BCR) after local curative intended treatment (e.g. radical prostatectomy, radiotherapy of the prostate or combination thereof) Cohort 2: non-metastatic castration-resistant prostate cancer (nmCRPC) or Cohort 3: metastatic hormone sensitive prostate cancer (mHSPC) or Cohort 4: metastatic castration-resistant prostate cancer (mCRPC) (irrespective of treatment choice, treatment line) * Patients who will receive a new line of systemic therapy at the time of study entry or up to 4 weeks thereafter. Regarding Cohort 4 this includes patients with a new diagnosis of mCRPC (=first line mCRPC) after either treatment for mHSPC or non-metastatic CRPC as well as patients with prior mCRPC treatments (2nd, 3rd, … line). * For Cohorts 1, 2 and 3: Disease proven by clinical measures (i.e. standard imaging) to be either unsuitable for local salvage treatment (e.g. surgery, radiotherapy) or local treatment is declined by the patient. * Patients, who are able and willing to sign the informed consent form Exclusion Criteria: • Patients who are not eligible for observation due to severe comorbidities or unavailability according to the treating physician
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Get notified about this study
Sign up to get updates when this study changes or when new studies for Biochemical recurrence of malignant neoplasm of prostate are added.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
53 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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"Brüder" Hospital St. Joseph Paderborn
RECRUITINGPaderborn, North Rhine-Westphalia, 33098, Germany
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"Vivantes Prostatazentrum" Hospital "am Urban"
RECRUITINGBerlin, Brandenburg, 10967, Germany
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Caritas-Hospital St. Josef
RECRUITINGRegensburg, Bavaria, 93053, Germany
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Center for Urology Boxberg
RECRUITINGNeunkirchen, Saarland, 66538, Germany
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City Hospital Dessau
RECRUITINGDessau, Saxony-Anhalt, 06847, Germany
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Hospital "Barmherzigen Brüder "Trier
RECRUITINGTrier, Rhineland-Palatinate, 54292, Germany
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Hospital Bayreuth GmbH
RECRUITINGBayreuth, Bavaria, 95445, Germany
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Hospital Kempten
RECRUITINGKempten (Allgäu), Bavaria, 87439, Germany
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Hospital Nürnberg North
RECRUITINGNuremberg, Bavaria, 90419, Germany
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Hospital Wetzlar
RECRUITINGWetzlar, Hesse, 35578, Germany
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Johanniter GmbH, Johanniterkrankenhaus
RECRUITINGBonn, North Rhine-Westphalia, 53113, Germany
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Johanniter Hosptal Bonn
RECRUITINGBonn, North Rhine-Westphalia, 53113, Germany
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MVZ Onco Medical GmbH Neustadt
RECRUITINGNeustadt am Rübenberge, Lower Saxony, 31535, Germany
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Marien Hospital Bergisch Gladbach,
RECRUITINGBergisch Gladbach, North Rhine-Westphalia, 51465, Germany
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Marien Hospital Herne, University Hospital der Ruhr-Universität Bochum
RECRUITINGHerne, North Rhine-Westphalia, 44625, Germany
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Medical Office for Urology
RECRUITINGBraunschweig, Lower Saxony, 38100, Germany
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Medical Office for Urology
RECRUITINGHerzberg am Harz, Lower Saxony, 37412, Germany
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Medical Office for Urology
RECRUITINGBayenthal, North Rhine-Westphalia, 50968, Germany
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Medical Office for Urology
RECRUITINGWürselen, North Rhine-Westphalia, 52146, Germany
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Medical Office for Urology "Urologicum"
RECRUITINGDuisburg, North Rhine-Westphalia, 47169, Germany
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Medical Office for Urology Altstadtquartier Magdeburg
RECRUITINGMagdeburg, Lower Saxony, 39104, Germany
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Medical Office for Urology Nürtingen
RECRUITINGNürtingen, Baden-Wurttemberg, 72622, Germany
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National Center for Tumor Dieseases (NCT) Heidelberg
RECRUITINGHeidelberg, Baden-Wurttemberg, 69120, Germany
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Praxisgemeinschaft f. Onkologie & Urologie
RECRUITINGWilhelmshaven, Lower Saxony, 26389, Germany
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St. Bernward Hospital Hildesheim
RECRUITINGHildesheim, Lower Saxony, 31134, Germany
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St. Bernward Krankenhaus GmbH
RECRUITINGHildesheim, Lower Saxony, 31134, Germany
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Studienpraxis Urologie
RECRUITINGNürtingen, Baden-Wurttemberg, 72622, Germany
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Univerity Hospital Schleswig-Holstein
RECRUITINGLübeck, Schleswig-Holstein, 23562, Germany
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Universital Hospital Gießen & Marburg GmbH, Site: Marburg
RECRUITINGMarburg, Hesse, 35043, Germany
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Universitiy Hospital Gießen und Marburg GmbH, Site: Gießen
RECRUITINGGiessen, Hesse, 35392, Germany
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Universitiy Hospital Halle
RECRUITINGHalle, Saxony-Anhalt, 06120, Germany
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University Hospital Aachen
RECRUITINGAachen, North Rhine-Westphalia, 52074, Germany
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University Hospital Augsburg
RECRUITINGAugsburg, Bavaria, 86156, Germany
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University Hospital Augsburg
RECRUITINGAugsburg, Bavaria, 86156, Germany
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University Hospital Bonn
RECRUITINGBonn, North Rhine-Westphalia, 53127, Germany
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University Hospital Düsseldorf
RECRUITINGDüsseldorf, North Rhine-Westphalia, 40225, Germany
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University Hospital Erlangen
RECRUITINGErlangen, Bavaria, 91054, Germany
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University Hospital Essen
RECRUITINGEssen, North Rhine-Westphalia, 45147, Germany
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University Hospital Frankfurt/Main
RECRUITINGFrankfurt am Main, Hesse, 60590, Germany
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University Hospital Halle
RECRUITINGHalle, Saxony-Anhalt, 06120, Germany
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University Hospital Hamburg-Eppendorf
RECRUITINGHamburg, Free and Hanseatic City of Hamburg, 20246, Germany
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University Hospital Jena
RECRUITINGJena, Thuringia, 07747, Germany
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University Hospital Leipzig
RECRUITINGLeipzig, Saxony, 04103, Germany
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University Hospital Magdeburg
RECRUITINGMagdeburg, Saxony-Anhalt, 39120, Germany
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University Hospital Mannheim
RECRUITINGMannheim, Baden-Wurttemberg, 68167, Germany
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University Hospital Rostock
RECRUITINGRostock, Mecklenburg-Vorpommern, 18057, Germany
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University Hospital Tübingen
RECRUITINGTübingen, Baden-Wurttemberg, 72076, Germany
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University Hospital Ulm
RECRUITINGUlm, Baden-Wurttemberg, 89081, Germany
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University Hospital Wuppertal
RECRUITINGWuppertal, North Rhine-Westphalia, 42283, Germany
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University Hospital Würzburg
RECRUITINGWürzburg, Bavaria, 97080, Germany
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Universitätsklinikum Freiburg
RECRUITINGFreiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
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Urban Hospital Karlsruhe
RECRUITINGKarlsruhe, Rhineland-Palatinate, 76133, Germany
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Urologie Altstadtquartier Magdeburg
RECRUITINGMagdeburg, Saxony-Anhalt, 39104, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A scanner in the operating room could show surgeons exactly where prostate cancer remains
- New PET tracer aims to light up hidden cancer targets
- Can daily adaptive radiotherapy spare healthy tissue in prostate cancer?
- Can a radioactive tracer and MRI reveal prostate Cancer's true extent?
- Five-Fraction radiation plus hormone therapy tested against High-Risk prostate cancer
- Can a 10-Hour eating window fight cancer fatigue?