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Can genes predict prostate cancer? new study follows High-Risk men for answers

NCT ID NCT03805919

First seen Nov 12, 2025 · Last updated Jun 19, 2026 · Updated 21 times

Summary

This study tracks 500 men aged 30–75 who have specific genetic changes linked to prostate cancer but have not been diagnosed. Researchers will monitor their health over time using yearly checkups, blood tests, and prostate MRIs every two years. The goal is to understand how these genetic factors affect cancer risk and whether they can guide future prevention or early detection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help identify which genetic changes most strongly predict prostate cancer, leading to better screening and prevention strategies.

What could go wrong

This is an observational study, not a treatment trial. It may take many years to yield clear results, and findings may not apply to all men or lead to immediate changes in care.

Conditions

The condition(s) this trial relates to.

Colorectal Neoplasms, Hereditary Nonpolyposis prostate cancer prostate neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.