Can Early-Life exposures shape lifelong health? a 1000-Family study aims to find out
NCT ID NCT04417283
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This study follows 1,000 pregnant women and their babies to understand how pregnancy and early-life exposures affect long-term health, school performance, and use of state services. Researchers will collect biological samples and health data from mothers and infants. The goal is to identify factors that may influence the health of mothers and babies, both in the short and long term.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- This study could help identify factors that influence the long-term health of mothers and babies, potentially guiding future prevention strategies.
- What could go wrong
- As an observational study, it cannot prove cause and effect. Results may take years to emerge and may not apply to broader populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2018
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Mother and/or infant participants will provide a series of biological specimens, including blood, urine, and microbiome samples. Additionally, each participant will wear a silicone wrist band each trimester to capture environmental exposures and will fill out study surveys related to diet, environmental exposures, and social factors.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * The subject has provided a signed Informed consent prior to any study procedures. * Maternal age at consent of ≥ 18 years old * Ability to understand English or Spanish * Willingness to comply with and be available for all protocol procedures * Singleton gestation \< 24 weeks 0 days * Receiving prenatal care at a Duke-affiliated Obstetrics clinic with the intent of delivering at Duke University Health System-affiliated hospital (including Duke University Hospital and Duke Regional Hospital) * Plans to have their infant seen at a Duke-affiliated Pediatrics practice after birth * Plans to remain in the area for two years after delivery Exclusion criteria: * Non-viable pregnancy * Having any condition that, in the opinion of the site investigators, would place the subject at unacceptable risk of injury or confound data interpretation
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Duke affiliated ObGyn clinics within Duke Health
Durham, North Carolina, 27710, United States
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