MRI heart scan may forecast future for heart muscle disease patients
NCT ID NCT02352129
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at 262 people with dilated cardiomyopathy, a condition where the heart muscle is weakened and enlarged. Researchers used a special MRI technique (T1 mapping) to measure scarring (fibrosis) in the heart. They wanted to see if the amount of scarring could predict serious events like death, heart transplant, or hospital stays over two years. The goal is to improve how doctors assess risk for these patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better ways to predict which patients with dilated cardiomyopathy are at higher risk of complications, helping doctors tailor treatment.
- What could go wrong
- This is an observational study, not a treatment trial. It may not change current care, and the findings might not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
262 people
The number who actually took part.
- Started
-
Dec 2011
- Finished
-
Jun 2017
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patient with dilated cardiomyopathy and typical symptoms of cardiac insufficiency at the time of the diagnosis: oedemas of lower limbs, dyspnoea, asthenia. * and of a reduction in the fraction of ventricular ejection left (awkward) 45 % measured in echocardiography ( modified Simpson biplane) and associated with a volume télédiastolic volume superior to the normal in echocardiography: \> 90ml / m2 ( modified Simpson biplane). Exclusion Criteria: * Patients to whom the dysfunction VG is secondary or in a secondary overload of pressures in a HTA or a severe valvulopathie is in a coronary infringement(achievement), proved by histories of infarct or gestures(movements) of revascularisation (bypass(decking), stent) and or coronary hurts at least bi tronculaires significant the severity of which can explain the ventriculaire failure.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cardiomyopathy, dilated are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Assistance Publique Hopitaux de Marseille
Marseille, 13354, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New pacing method may help more heart failure patients
- Heart MRI model could predict deadly risks in DCM patients
- Could a common ED drug help kids with heart failure?
- New heart study aims to cut unnecessary pacemaker implants by half
- Heart rhythm showdown: ablation may beat drugs for ventricular tachycardia
- New study aims to predict which heart patients will respond to therapy