Can we spot Parkinson's before it starts? major screening study launches
NCT ID NCT04724941
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is screening 2,000 people aged 50 to 99 who may have a higher risk of developing Parkinson's disease. Researchers will follow participants for five years to track early changes in risk markers and symptoms. The goal is to better understand how Parkinson's develops and to improve how doctors share early risk information with patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify early markers of Parkinson's disease and improve how we disclose risk to individuals.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to direct benefits for participants, and the findings may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 2,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2021
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
General population
- Ages
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50 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age between 50 and 99 Exclusion Criteria: * Presence of clinical PD at the time of study inclusion * Other significant neurologic diseases affecting the central nervous system (e.g. Multiple sclerosis) * other significant diseases e.g. orthopaedic diseases affecting quantitative motor assessment * in case of participation in the lumbal puncture substudy: contraindications for the performance of lumbal puncture (bleeding tendency, intake of anticoagulants)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department for Neurology, University of Kiel
RECRUITINGKiel, 24118, Germany
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Other studies related to the condition(s) this trial covers.
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