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Could good bacteria curb alcohol cravings?

NCT ID NCT07510113

Symptom relief Sponsor: Loughborough University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Sep 16, 2026 · Updated 3 times

Summary

This study tests whether taking a probiotic supplement for four weeks can reduce alcohol cravings and improve thinking, mood, and gut health in people with alcohol use disorder. 38 participants are randomly assigned to receive either the probiotic or a placebo, and neither they nor the researchers know who gets what. The goal is to see if probiotics could be a helpful addition to current treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
probiotic supplement
What this could lead to
If it works, this could point toward a simple, low-cost supplement to help reduce alcohol cravings and support mental health in people with alcohol use disorder.
What could go wrong
This is a very small pilot trial with only 38 participants, so results may not be reliable or apply to everyone. It is too early to know if probiotics truly help.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

38 people

The number who actually took part.

Started

Dec 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * A self-reported history of heavy drinking * At least one heavy drinking episode (≥8 units) in the last 28 days Exclusion Criteria: * Participants being under 18 years of age * Supplementation of probiotics or prebiotics within the past 4 weeks * Antibiotic use within the past 4 weeks * Major psychiatric conditions diagnosed e.g., bipolar disorder, schizophrenia * Current pregnancy or breastfeeding * Having had a heavy drinking episode (≥8 units) in the last 12 hours

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol use disorder

Contacts and locations

Locations

  • Loughborough University

    Loughborough, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.