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Probiotic LB42 shows promise for gut and immune boost in healthy adults

NCT ID NCT06873438

Knowledge-focused Sponsor: Wecare Probiotics Co., Ltd. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether taking a daily probiotic called Lactobacillus LB42 can improve gut and immune function in healthy adults aged 18 to 45. Fifty-two participants took either the probiotic or a placebo for a period, and researchers measured changes in immune markers and gut bacteria in their stool. The goal was to see if this food supplement is safe and effective for supporting overall health.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

52 people

The number who actually took part.

Started

Mar 2025

Finished

Aug 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-45 years 2. Willing to undergo 3 follow-up visits during the intervention period 3. Willing to provide 2 blood, urine, and stool samples during the intervention period 4. Willing to self-administer one of the probiotics/placebo once daily during the intervention period 5. Good eyesight, able to read and write, and can wear glasses 6. Have good hearing and be able to hear and understand all instructions during the intervention Exclusion Criteria: 1. Suffering from digestive disorders, mainly gastrointestinal disorders (celiac disease, ulcerative colitis, Crohn's disease) 2. Has a severe neurological condition (epilepsy, stroke, severe head trauma, meningitis within the past 10 years, brain surgery, brain tumor, prolonged coma - excluding general anesthesia) 3. Has received/is receiving treatment for the following psychiatric disorders: alcohol/drug/substance abuse dependence, schizophrenia, psychosis, bipolar disorder 4. Take medication for depression or low mood 5. Suffering from internal organ failure (heart, liver, or kidney failure, etc.) 6. Radiotherapy or chemotherapy in the past 7. Surgery/procedure under general anesthesia within the past three years, or planned to undergo a procedure/procedure under general anesthesia within the next 3 months during this trial 8. Have had hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intestinal and immune function improved

Contacts and locations

Locations

  • Xu fei

    Zhengzhou, Henan, 210095, China