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Probiotic drops may stop antibiotic tummy troubles in children

NCT ID NCT07234448

First seen Nov 18, 2025 · Last updated Jun 20, 2026 · Updated 31 times

Summary

This study tests whether a probiotic supplement in oral drops can prevent diarrhea in children aged 0-12 who are taking common antibiotics like amoxicillin. One thousand children will receive either the probiotic or a placebo during their antibiotic course, and researchers will track how many develop diarrhea. The goal is to see if this simple addition to treatment can reduce a frequent and uncomfortable side effect.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bifidobacterium breve PRL2020 probiotic drops

What this could lead to

If it works, this could offer a simple, safe way to prevent antibiotic-related diarrhea in children, reducing discomfort and doctor visits.

What could go wrong

This is an early-stage trial with no phase designation, so results are uncertain. The probiotic is only given during the antibiotic course, and long-term effects are not studied.

Conditions

The condition(s) this trial relates to.

Clostridium difficile colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.