Former pro athletes get heart check with AI
NCT ID NCT07460583
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will use AI-guided CT scans to look for signs of heart disease in 100 former high-intensity athletes, like NFL alumni or Division I players, aged 30 and older. The goal is to find out how common coronary artery disease is in this group and understand the types of plaque buildup. Participants will not receive any treatment, but the results may help improve future heart screening for retired athletes.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Former professional or collegiate high-intensity athletes (e.g., NFL alumni, Division I athletes, or equivalent competitive-level participants). * Age ≥30 years Exclusion Criteria: * eGFR \<40 mL/min/1.73 m² * Known iodinated contrast allergy * Weight \>450 lbs. (scanner table limit) * Inability to hold breath \>10 seconds * Uncontrolled arrhythmia * Contraindication to beta-blocker, Calcium Channel Blockers and nitroglycerin * Taking part in another research study that has not given their permission to participate in this one * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Baylor Scott & White The Heart Hospital- Plano
Plano, Texas, 75093, United States