Egg donation pregnancy study seeks clues to dangerous blood pressure disorder
NCT ID NCT07263490
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 462 women pregnant after egg donation or standard IVF to learn why pre-eclampsia is more common in egg donation pregnancies. Participants give blood samples and have regular check-ups throughout pregnancy. The goal is to find early warning signs and improve care for mothers and babies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 462 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2024
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Study population consists of women undergoing fertility treatment with IVF with either donated oocytes (Preg OD cohort) or autologous oocytes (Preg IVF cohort)
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \> 18 years * BMI \< 35 kg/m2 * Normal wet smear within the past three years * Both nulli- and multiparous * Singletons and multiple gestations Exclusion Criteria: * Age \< 18 years * BMI \> 35 kg/m2 * HIV/ hepatitis * Essential hypertension * Chronic kidney disease * Undiagnosed vaginal bleeding * Uterine malformations * Persisting ovarian cysts * Tumors in hypothalamus, pituitary, thyroid, or adrenal glands. * Previous breast cancer * Known BRCA 1 or 2 gene * Unregulated thyroid disease * Cardiovascular disease * Breast feeding * Present or previous chemotherapy/radiation therapy * Present or previous malignant disease * Smoking * Alcohol/drug abuse
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
6 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Aleris Fertility
RECRUITINGSøborg, 2860, Denmark
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Copenhagen Fertility Center
RECRUITINGCopenhagen, 2400, Denmark
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Fertility Clinic, Herlev / Gentofte Hospital
RECRUITINGHerlev, 2730, Denmark
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Fertility Clinic, Rigshospitalet
RECRUITINGKøbenhavn Ø, 2100, Denmark
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Sellmer Klinik
RECRUITINGKøbenhavn S, 2300, Denmark
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Trianglen Fertility Clinic
RECRUITINGHellerup, 2900, Denmark
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Other studies related to the condition(s) this trial covers.
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- Can almonds tame overnight blood sugar in pregnancy?
- Citrulline: a potential key to prolonging pregnancy in pre-eclampsia?
- Scientists test whether calmer mothers make better milk
- Can exercise shield pregnant women from preeclampsia?