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Brain scans reveal how a 6-Week program may curb teen risky behavior

NCT ID NCT03370393

Knowledge-focused Sponsor: University of California, Irvine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a 6-week, technology-based family program called PAAS could change brain activity linked to risky behavior in African-American teens. 146 teens and their parents participated, with brain scans and questionnaires before and after the program. The goal was to see if the program improves emotional and cognitive regulation, which could help prevent behaviors like HIV risk and violence.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Pathways for African-Americans' Success (PAAS) program
What this could lead to
If successful, this could show how a behavioral program changes brain function to reduce risky behaviors like HIV risk and violence in African-American teens.
What could go wrong
This is a small, completed study focused on brain changes, not direct behavior outcomes. Results may not apply to all teens or lead to a proven prevention method.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

146 people

The number who actually took part.

Started

Dec 2017

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

11 to 14 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subject is of African-American racial status (self-reported) * Subject can speak and read English * Subject and parent/legal guardian agree to participate in the 6-week PAAS program * Subject and parent/legal guardian agree to complete all assessments * Subject must meet MRI safety eligibility Exclusion Criteria: * Subject has a major medical problem (e.g. neurological disorders) * Subject is on medication(s) that affects the central nervous system * Subject has behavioral/emotional problems at a clinical level (parent and/or youth report) * Subject is pregnant or suspected of being pregnant (based on pregnancy test) * Subject is color-blind * Subject has claustrophobia * Subject has metallic implants * Subject drinks alcohol in the week prior to entry into the study (based on urine drug screen) * Subject uses drugs in the week prior to entry into the study (based on urine drug screen)

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Conditions

The condition(s) this trial relates to.

Adolescent Behavior Risk-Taking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adolescent behavior Risk-taking

Contacts and locations

Locations

  • University of California, Irvine

    Irvine, California, 92617, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.