Parenting coaching shows promise in preventing postpartum depression
NCT ID NCT03283254
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a behavioral program called PREPP, which provides coaching sessions to pregnant women at risk for postpartum depression. The program focuses on improving infant sleep and reducing fussiness, aiming to lower depression risk. 216 women participated, receiving either the coaching or standard care. The goal was to see if this approach could prevent or lessen postpartum depression symptoms.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Practical Resources for Effective Postpartum Parenting (PREPP) - a behavioral intervention (psychotherapy coaching sessions)
- What this could lead to
- If successful, this approach could offer a practical, non-drug way to prevent postpartum depression in at-risk women, improving outcomes for both mothers and infants.
- What could go wrong
- This is a completed trial, but results may not apply to all populations. The intervention is behavioral and may not work for everyone; larger studies are needed to confirm effectiveness.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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216 people
The number who actually took part.
- Started
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Feb 2018
- Finished
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Feb 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Healthy pregnant women between 18-45 years old (based on self report) 2. A score of ≥19 on the Predictive Index of Postnatal Depression (PIPD), indicating risk for developing postpartum depression or score of ≥7 on the Edinburgh Postnatal Depression Scale 3. A healthy, singleton pregnancy (based on self report) 4. English speaking (based on self report) 5. Receiving standard prenatal care (based on self report) Exclusion Criteria: 1. Multi-fetal pregnancy (based on self-report) 2. Smoking, illicit drug use, or alcohol use during pregnancy (based on self-report) 3. Acute medical illness or significant pregnancy complication (based on self-report) 4. Currently in weekly, individual psychotherapy, including psychopharmacology (based on self report) 5. Psychotic d/o; Bipolar I; Major Depressive d/o (based on M.I.N.I.)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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New York State Psychiatric Institute
New York, New York, 10032, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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