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Which drug stops Post-Surgery nausea better? new study has answers

NCT ID NCT07426081

Symptom relief Sponsor: Patel Hospital, Pakistan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two medications, dexmedetomidine and dexamethasone, to see which works better at preventing nausea and vomiting after laparoscopic gallbladder removal. 68 adults took part in this double-blind trial. The goal is to improve patient comfort after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

68 people

The number who actually took part.

Started

Jun 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Both male and female patients will be included 2. Patient between the age of 18 to 60 years. 3. Patient undergoing elective Laparoscopic Cholecystectomy. 4. Patients with American Society of Anesthesiologists (ASA) physical status I and II. Exclusion Criteria: 1. Patient not willing to participate in study. 2. Patients with a history of allergy to dexmedetomidine and dexamethasone. 3. Patients having motion sickness and history of PONV in past anesthesia experience. 4. Patients receiving antiemetic drugs during the last 48 hours before laparoscopic cholecystectomy. 5. Patients with body mass index ≥ 30 kg/m2 6. Patients with emergency laparoscopic cholecystectomy. 7. Laparoscopic cholecystectomy lasts for more than one hour. 8. Laparoscopic cholecystectomy converting to open cholecystectomy.

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Conditions

The condition(s) this trial relates to.

Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative nausea and vomiting

Contacts and locations

Locations

  • Marium Rafiq

    Karachi, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.