Can a simple nerve block stop chronic pain after C-Section?
NCT ID NCT05602038
First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study tested two different pain relief methods given during a C-section to see if they could prevent chronic pain that sometimes lasts for months or years. One method was a nerve block (quadratus lumborum block) and the other was a small dose of morphine injected into the spinal fluid. The trial involved 100 women having planned C-sections and measured their pain levels and need for extra painkillers afterward.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Quadratus lumborum block (nerve block procedure) and intrathecal morphine (painkiller injected into spinal fluid)
- What this could lead to
- If successful, this could point to a simple way to prevent chronic pain after cesarean sections, improving long-term recovery for many women.
- What could go wrong
- This is a small, completed trial (100 participants) and results may not apply to all women. The nerve block and spinal morphine also carry risks like infection or side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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100 people
The number who actually took part.
- Started
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Feb 2023
- Finished
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Dec 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients admitted to the operating theatre for elective caesarean section Exclusion Criteria: * lack of informed consent * Allergy to drugs used during the study * Depression and epilepsy that required antidepressants or anticonvulsants * known coagulopathy as a contraindication for spinal anesthesia
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Menoufia University
Menoufia, Menoufia, 32817, Egypt
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