New study aims to prevent brain damage in preterm infants after bleeding
NCT ID NCT07157020
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at 300 premature infants who develop fluid buildup in the brain after a bleed. Researchers want to see if starting drainage earlier than usual can reduce the risk of death or long-term developmental issues like cerebral palsy. The approach uses ultrasound imaging and repeated lumbar punctures to guide treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ommaya capsule implantation (lumbar puncture drainage)
- What this could lead to
- If successful, this could establish a better timing for draining fluid from the brain after a bleed, potentially reducing the risk of long-term developmental problems in preterm infants.
- What could go wrong
- This is an early-stage study with no results yet. The new intervention threshold may not improve outcomes and could carry risks from the drainage procedure itself.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Up to 28 days
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Gestational age: 23+0 weeks to 36+6 weeks; * Post-hemorrhagic hydrocephalus is confirmed by cranial ultrasound or other cranial imaging examinations. * No cerebrospinal fluid drainage treatment was received before enrollment. Exclusion Criteria: * Excluding secondary IVH, including but not limited to congenital malformations, vitamin K1 deficiency, abnormal coagulation function, etc. * Excluding hydrocephalus caused by other reasons, including but not limited to infection, congenital malformations, intracranial space-occupying lesions, etc. * Treatment before diagnosis of hydrocephalus after intraventricular hemorrhage or suspected presence of central nervous system infection.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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