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New trial aims to stop a deadly cancer before it starts

NCT ID NCT06698003

First seen Mar 26, 2026 · Last updated Jun 23, 2026 · Updated 14 times

Summary

This phase 2 study tests whether the drug mogamulizumab can prevent adult T-cell leukemia/lymphoma (ATL) in people infected with HTLV-1 who are at high risk. About 134 participants will receive low doses of the drug over several weeks. The goal is to see if it can reduce the virus's activity enough to stop cancer from developing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Memorial Sloan Kettering Bergen (All Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (All protocol activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (All protocol activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (All protocol activities)

    RECRUITING

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (All protocol activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering at Basking Ridge (All protocol activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mogamulizumab

What this could lead to

If successful, this could offer a way to prevent a rare but aggressive blood cancer in people carrying the HTLV-1 virus.

What could go wrong

This is an early phase 2 trial with only 134 participants, so results may not apply to everyone. The drug may cause side effects or fail to reduce cancer risk long-term.

Conditions

The condition(s) this trial relates to.

lymphoma Precursor T-Cell Lymphoblastic Leukemia-Lymphoma T-cell leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.