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Common prostate drugs ease kidney stone surgery, study finds

NCT ID NCT07202923

Symptom relief Sponsor: St. Luke's Clinical Hospital, Russia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether taking a type of medication called alpha-blockers (tamsulosin or silodosin) before a specific kidney stone surgery (RIRS) makes it easier for doctors to insert a needed tube and reduces damage to the tube that carries urine from the kidney to the bladder. The study involved 140 adults with small kidney stones. The results showed that patients who took the medication had a higher success rate for tube insertion and less injury to the urinary tract, especially in patients over 59 years old or with a BMI over 25.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

140 people

The number who actually took part.

Started

Jul 2021

Finished

Jun 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This is an interventional RCT. Population characteristics are described in Eligibility Criteria and Arms sections

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 years and older * Kidney stone size: ≤2 cm * Stone density \>1000 Hounsfield units * Sterile urine culture Exclusion Criteria: * Congenital anomalies of the urinary tract * Urinary tract infections * Upper urinary tract obstruction * Prior reconstructive surgeries on the upper urinary tract

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Conditions

The condition(s) this trial relates to.

injury nephrolithiasis urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nephrolithiasis primary Pharmacologic facilitation of ureteral access Retrograde intrarenal surgery Ureteral access sheath Ureteral injury Ureteral injury secondary as this assesses prevention Urolithiasis

Contacts and locations

Locations

  • St. Luke's Clinical Hospital

    Saint Petersburg, Outside U.S./Canada, Russia

More trials for these conditions

Other studies related to the condition(s) this trial covers.